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SANDOZ AG(31)
SANDOZ AG [CH](27)
SCHERING CORPORATION(24)
Enzon Pharmaceuticals, Inc.(6)
Elan Pharma International Ltd.(5)
SANDOZ AG [CH](5)
DE SOUZA DOMINIC [AT](5)
BHUTA SACHIN [IN](4)
PISE ABHINAY C [IN](4)
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专利信息
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[药品] 包含 'Posaconazole'
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公开号
公开日
申请号
申请日
1.
EP2318396B1
2012/10/24
专利标题
:A crystalline form of posaconazole
专利权人
:
SANDOZ AG
;
The present invention relates to crystalline form IV of posaconazole and pharmaceutical compositions comprising the same. The pharmaceutical composition can be used to treat or prevent fungal infections.
2.
NZ573555A
2012/9/28
NZ20070573555
2007/5/22
专利标题
:NANOPARTICULATE POSACONAZOLE FORMULATIONS
专利权人
:
ELAN PHARMA INT LTD
;
Disclosed is a stable nanoparticulate posaconazole composition in an oral dosage form comprising: (a) particles of a posaconazole or a salt or derivative thereof having an effective average particle size of less than about 1000 nm
3.
CN102643194A
2012/8/22
CN2012183473
2012/3/27
专利标题
:Preparation method of posaconazole intermediate
专利权人
:
UNIV FUZHOU
;
4.
NZ588460A
2012/7/27
NZ20090588460
2009/4/15
专利标题
:ORAL PHARMACEUTICAL COMPOSITIONS IN A SOLID DISPERSION COMPRISING PREFERABLY POSACONAZOLE AND HPMCAS
专利权人
:
SCHERING CORP
;
A composition comprising posaconazole dissolved or molecularly dispersed in a hydroxypropylmethyl-cellulose-derivative polymer is disclosed, wherein, when an amount of the composition comprising at least about 100 mg of posaconazole is administered orally to a human under fasted conditions, at least one of the following PK median parameters are observed: Cmax in at least about 300 ng/mL
5.
WO2011144657A8
2012/7/26
专利标题
:Purification of posaconazole and of posaconazole intermediates
专利权人
:
SANDOZ AG
;
The present invention relates to a process for the preparation of a hydrogen chloride (HC1) salt of a compound of formula (I) wherein Y.sub.1 and Y.sub.2 are independently F or C1 preferably F said compound of formula (I) containing the cis-isomer and the trans-isomer wherein the process comprises (1) providing the compound of formula (I) comprised in a first suitable solvent; and (2) treating the compound of formula (I) comprised in the first suitable solvent with HC1 comprised in a second suit...
6.
EP2451805A1
2012/5/16
EP20100729907
2010/7/9
专利标题
:A CRYSTALLINE FORM OF POSACONAZOLE
专利权人
:
SANDOZ AG [CH]
;
7.
US2012101277A1
2012/4/26
US201013379060
2010/7/9
专利标题
:CRYSTALLINE FORM OF POSACONAZOLE
专利权人
:
WIESER JOSEF [AT]
;
PICHLER ARTHUR [AT]
;
HOTTER ANDREAS [AT]
;
GRIESSER ULRICH [AT]
;
LANGES CHRISTOPH [AT]
;
SANDOZ AG [CH]
;
The present invention relates to crystalline form II-S, its preparation and its use to prepare other crystalline forms of posaconazole, in particular crystalline form IV of posaconazole.
8.
US20120101277A1
2012/4/26
专利标题
:Crystalline form of posaconazole
专利权人
:
SANDOZ AG
;
The present invention relates to crystalline form II-S its preparation and its use to prepare other crystalline forms of posaconazole in particular crystalline form IV of posaconazole.
9.
WO2011158248A3
2012/3/8
专利标题
:Process for preparation of posaconazole and crystalline polymorphic form v of posaconazole
专利权人
:
Glenmark Generics Limited
;
Disclosed are a process for preparation of an antifungal agent posaconazole and crystalline polymorphic form V of antifungal agent posaconazole.
10.
WO2012005973A1
2012/1/12
WO2011US41715
2011/6/24
专利标题
:POSACONAZOLE INTRAVENOUS SOLUTION FORMULATIONS STABILIZED BY SUBSTITUTED BETA-CYCLODEXTRIN
专利权人
:
SCHERING CORP [US]
;
HEIMBECHER SUSAN K [US]
;
MONTEITH DAVID [US]
;
The present invention relates to aqueous solutions useful as pharmaceutical compositions of posaconazole for intravenous administration. These compositions include a solubilizing agent, such as a modified ss-cyclodextrin in an acidified solution, which can also include a chelating agent such as disodium edetate (EDTA). In clinical trials, a 200 mg posaconazole dose of the selected composition was found to achieve acceptable pharmacokinetic properties.
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