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Euro-celtique S.a.(84)
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[药品] 包含 'Naloxone'
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1.
FR2428439A1
1980/1/11
FR19790014943
1979/6/12
专利标题
:Composition pharmaceutique pour le traitement therapeutique des etats de frigidite et d'impuissance sexuelle.
专利权人
:
Tecnofarmaci Spa
;
PL'invention a pour objet une composition pharmaceutique pour le traitement de la frigidité et de l'impuissance sexuelle. Le composé actif dans la composition pharmaceutique est un composé qui exerce une action antagoniste ou inhibitrice vis-à-vis des récepteurs opiacés; la composition permet le traitement de la frigidité et de l'impuissance aussi bien d'origine naturelle que du type provoqué par des médicaments analogues à la morphine. Les composés préférés sont la naloxone la naltrexone et la ...
2.
US4181726A
1980/1/1
US05/961239
1978/11/16
专利标题
:Method of alleviating pruritis
专利权人
:
Bernstein, Joel E
;
An improved method of relieving severe itching associated with conditions such as Hodgkin\'s Disease mycosis fungoides intractable pruritis and the like comprising administering an effective dosage of naloxone to a patient suffering from such itching.
3.
US4141897A
1979/2/27
US05/751570
1976/12/20
专利标题
:N-dealkylation of n-alkyl-14-hydroxymorphinans and derivatives thereof
专利权人
:
Salflex, Inc.
;
There is provided a novel high yield method of dealkylating N-alkylated 14-hydroxymorphinans and derivatives thereof including inter alia oxymorphone and oycodone. There are thus provided inter alia more efficient routes for the formation of naloxone naltrexone and nalbuphine. In the principal step of the process the dealkylation using certain oxycarbonyl halides (or haloformates) is carried out on the N-alkyl-14-acyloxy-morphinan which it is desired to dealkylate.
4.
US4098778A
1978/7/4
US05/811651
1977/6/30
专利标题
:.beta.-endorphin analog
专利权人
:
Regents Of The University Of California The, 2200 University Avenue, Berkeley Ca 94720
;
The .beta.-endorphin analog .beta.-endorphin (6-31) although lacking the enkephalin moiety i.e. .beta.-endorphin (1-5) exhibits analgesic activity which is not reversed by naloxone.
5.
US3966940A
1976/6/29
US05/609847
1975/9/2
专利标题
:Analgetic compositions
专利权人
:
Bristol-myers Company
;
Orally effective analgetic compositions have been developed which are useful in the prevention of drug abuse because upon parenteral administration they do not produce analgesia euphoria or physical dependence. Such compositions comprise an orally active strong analgetic in oral dosage form and containing for each analgetic dose of the analgetic agent an amount of naloxone sufficient upon parenteral administration of said oral dosage form to negate the analgetic euphoretic and dependence produci...
6.
GB1390772A
1975/4/16
GB19720011319
1972/3/10
专利标题
:Oral narcotic composition
专利权人
:
Endo Laboratories Inc
;
1390772 Narcotic compositions ENDO LABORATORIES INC 10 March 1972 [7 May 1971] 11319/72 Heading A5B Pharmaceutical compositions comprise: (a) a compound having substantial narcotic activity both orally and by injection selected from oxycodone hydrocodone codeine propoxyphene and pentazocine and salts thereof and (b) a narcotic antagonist which is substantially less active orally than by injection selected from: (i) naloxone and its pharmaceutically acceptable salts (ii) N-cyclopropylmethyl-7 8-d...
7.
GB1353815A
1974/5/22
GB19710032077
1971/7/8
专利标题
:Analgetic composition
专利权人
:
BRISTOL MYERS CO
;
1353815 Analgesic compositions BRISTOLMYERS CO 8 July 1971 [3 Aug 1970] 32077/ 71 Heading A5B Abuse of an addictive orally active analgesic may be reduced by compounding it with naloxone in an amount sufficient to eliminate its analgesic or euphoric action when administered parenterally but insufficient to eliminate its analgesic or euphoric action when administered orally. Analgesics specified include meperidine oxymorphone dextropropoxyphene methadone levorphanol phenazocine profadol codeine -...
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