A formulation for example an oil-in-water emulsion comprising an amphoteric surfactant alkoxylated cetyl alcohol and a polar drug. The drug may be sodium cromoglycate or nedocromil sodium. The formulation may be useful in the treatment of skin disease such as atopic dermatitis.

PROBLEM TO BE SOLVED: To provide a composition which improves the skin penetration of sodium cromoglycate to be used in treating skin diseases such as atopic dermatitis. SOLUTION: A formulation for example an oil-in-water emulsion comprises an amphoteric surfactant an alkoxylated cetyl alcohol and a polar drug. The drug is sodium cromoglycate or nedocromil sodium. This formulation is useful in the treatment of skin diseases such as atopic dermatitis. COPYRIGHT: (C)2009JPO&INPIT

The use of solid pharmaceutically acceptable salts of cromoglycic acid and/or nedocromil as carriers in a therapeutically and prophylactically inefficacious amount in suspension aerosol formulations of pharmaceutical active compounds improves the dispersion properties increases the chemical and physical stability of moisture-sensitive active compounds makes possible a more accurate dosage in particular even of low-dose active compounds and as a rule permits the abandonment of surface-active agen...

Diseases of the colon are treated by oral ingestion of a unit dosage form containing a mast cell stabilizer as an active agent. The dosage form is targeted for delivery of the active agent to the colon or when in an immediate release formulation such as a fast-dissolving tablet powder or effervescent the targeted release is upon ingestion. The dosage form comprise at least one mast cell stabilizer such as but not limited to ketotifen nedocromil sodium cromolyn sodium and antihistamines which ha...

Diseases of the colon are treated by oral ingestion of a unit dosage form containing a mast cell stabilizer as an active agent. The dosage form is targeted for delivery of the active agent to the colon or when in an immediate release formulation such as a fast-dissolving tablet powder or effervescent the targeted release is upon ingestion. The dosage form comprise at least one mast cell stabilizer such as but not limited to ketotifen nedocromil sodium cromolyn sodium and antihistamines which ha...

Diseases of the colon are treated by oral ingestion of a unit dosage form containing a mast cell stabilizer as an active agent. The dosage form is targeted for delivery of the active agent to the colon or when in an immediate release formulation such as a fast-dissolving tablet powder or effervescent the targeted release is upon ingestion. The dosage form comprise at least one mast cell stabilizer such as but not limited to ketotifen nedocromil sodium cromolyn sodium and antihistamines which hav...

A formulation for example an oil-in-water emulsion comprising an amphoteric surfactant alkoxylated cetyl alcohol and a polar drug. The drug may be sodium cromoglycate or nedocromil sodium. The formulation may be useful in the treatment of skin disease such as atopic dermatitis.

Formulación para inhalación exenta de gas propulsor de bromuro de tiotropio o monohidrato de bromuro de tiotropio disuelto en agua o en una mezcla de agua y etanol y a los aerosoles inhalables exentos de gas propulsor que resultan de ello. Reivindicación 1: Preparado líquido de medicamentos exento de gas propulsor a base de por lo menos dos sustancias activas combinables que contiene; una sal de tiotropio como una de las sustancias activas en una concentración referida al tiotropio comprendida e...

Topical ophthalmic anti-allergy drugs are identified by the extent of their interaction with a phospholipid model membrane. Disclosed are topically administrable ophthalmic formulations containing amphipathic anti-allergy compounds at concentrations such that the drugs have Surface Activity Ratings from about 2-11. Provided the drug is not selected from the group consisting of olopatadine; ketotifen; emedastine; pheniramine; pyrilamine; cromolyn; nedocromil; and levocabastine.