The present invention provides a process for preparing orlistat from amino orlistat using Pivaloyl Formic Anhydride (PFA) as an alkanoylating agent.

The present invention relates to the stereoselective synthesis of (4aS7aS)-octahydro-1H-pyrrolo[34-b]pyridine as well as the conversion thereof to give Moxifloxacin. Particularly the present invention relates to a method for the synthesis of (4aS7aS)-octahydro-1H-pyrrolo[34-b]pyridine of formula (I) comprising: (a) the optical resolution by enzymatic hydrolysis of the intermediate dialkyl-1-alkylcarbonylpiperidine-23-dicarboxylate racemate of formula (II) to give following isolation the intermed...

The present invention relates to a novel manufacturing process of pharmaceutically active compound of formula I used as a long-acting anticholinergic bronchodilator. Starting from oxalic acid derivative of formula III the invention describes preparation of a novel cyclic anhydride of formula II which is very efficient precursor in the synthesis of Tiotropium bromide (compound of formula I).

A process for hydrogenating acetic acid to form of ethyl acetate and mixtures of ethyl acetate and ethanol. The hydrogenation is done in the presence of catalyst preferably on a support that optionally includes a support modifier.

A process for selective formation of ethanol and/or ethyl acetate from acetic acid by hydrogenating acetic acid in the presence of a Pt/Sn catalyst or a Re/Pd catalyst. The catalyst may further comprise a support modifier to improve selectivity for the desired product.

Purifying and/or recovery of ethanol from a crude ethanol product obtained from the hydrogenation of acetic acid from an feed stream comprising water. The presence of water does not significantly impact acid conversion or selectivity to ethanol. Further the addition of water allows for improved recovery of ethanol.

Provided in the present invention are a cocrystal of piperacillin sodium and sulbactam sodium and a preparation method therefor, as well as pharmaceutical compositions containing the same and uses thereof in treating infections caused by drug-resistant bacteria, such as a "super bacterium" producing NDM-1 and the like. The cocrystal of piperacillin sodium and sulbactam sodium contains diffraction angles of 14.24 DEG , 16.58 DEG , 16.79 DEG , 17.77 DEG , 19.20 DEG , 20.21 DEG , 20.39 DEG , 23.06 ...

The invention features pharmaceutically acceptable salts of cefdinir, including primary, secondary, and tertiary amine salts of cefdinir, and preparation methods, and pharmaceutical compositions including cefdinir. The invention also features water dispersible pharmaceutical dosage forms including cefdinir as active agent and methods for preparing the dosages. The invention also features tablet forms of cefixime characterized in that the tablets are in effervescent form. The invention also featu...

Disclosed is a cefuroxime sodium crystal compound and a composition powder injection thereof, wherein the crystal form of cefuroxime sodium is amorphous and the preparation method thereof is as follows: reacting cefuroxime acid with sodium bicarbonate to obtain a solution and adding active carbon to discolor it, and then quick-freezing for 2 hours at -40-50 DEG C after sterile filtration using a filter membrane, followed by vacuum drying. The components of the cefuroxime sodium composition powde...