This invention relates to the treatment of androgen receptor-positive breast cancer in a subject, for example a female subject. Accordingly, this invention provides methods of: a) treating a subject suffering from breast cancer

Disclosed are methods and compositions for inhibiting the growth of a tumor (e.g., a malignant tumor) in a subject. In particular, combination therapies for treating a tumor in a subject by co-administering an agent selected from i) an effective amount of an anti-estrogen agent

POSITIVELY CHARGED WATER-SOLUBLE PRODRUGS OF ACETAMINOPHEN AND RELATED COMPOUNDS WITH VERY FAST SKIN PENETRATION RATE The novel positively charged pro-drugs of acetaminophen, acetaminosalol, and related compounds in the general formula (1) 'Structure 1' were designed and synthesized. The positively charged amino groups of these pro-drugs not only largely increases the solubility of the drugs, but also bonds to the negative charge on the phosphate head group of membranes and pushes the pro-drug i...

The process of the present invention pertains to a process wherein a liquid feed comprising monochloroacetic acid, dichloroacetic acid,and optionally acetic acid and/or trichloroacetic acid is subjected to a catalytic hydrodechlorination step by contacting it with a source of hydrogen in the presence of a solid heterogeneous hydrogenation catalyst situated in a fixed catalyst bed, wherein the liquid feed is fed to the top of avertical tubular reactor at a superficial mass velocity of between and...

The present invention pertains to a process for the purification of a substantially water-free liquid feed comprising monochloroacetic acid, dichloroacetic acid, optionally acid chlorides, optionally anhydrides, and optionally acetic acid, which comprises the steps of (a) adding water to the liquid feed so that a liquid feed is obtained comprising between 0.01 and 5% by weight of water, based on the total weight of the liquid feed, and (b) subsequently subjecting the liquid feed obtained in step...

Silk protein composite coating solution and its preparation method and application. In weight percent, silk protein complex coating liquid is constituted by the following substances: 2 to 10% of the crosslinking agent, 0.5 to 2% acetic acid, 10 to 20% of the silk protein, the remainder being water. The method for preparation of silk protein composite coating solution has these steps: (1) preparation of the silk protein

Stabilised amorphous form of the compound of formula (I): Medicaments.

FIELD: process engineering.SUBSTANCE: invention relates to powder metallurgy, particularly, to activation of disperse aluminium powder combustion and can be used in various branches of industry. Proposed method comprises impregnation of initial powder with activator based on vanadium oxide compound. Gel is used as said activator containing 4.0-8.2 g/l of vanadium obtained by melting of vanadium oxide or vanadium oxide and lithium or sodium carbonate or vanadium oxide and boric acid or mix thereo...

The invention relates to a linerless label web for labels comprising a face having a first surface and a second surface, and an non tacky adhesive layer arranged on the second surface of the face having a static friction coefficient less than 0.8 against aluminium at room temperature. The invention also relates to use of the label web, to a method for attaching a label to an item, and to a combination of an item and a label. Preferably, the adhesive layer comrises ethylene vinyl acetate (EVA), s...

, The present invention provides crystalline forms, including an anhydrate form, of cabazitaxel and processes for the preparation of these forms, designated as Forms C1, C2, C3, C4, C5, C6, C7, C8, C8b, C9 and C9p.