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ABBOTT LAB [US](18)
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HOFFMANN LA ROCHE(14)
ORTHO CLINICAL DIAGNOSTICS INC [US](13)
JANSSEN PHARMACEUTICA NV [BE](13)
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UNIV CALIFORNIA [US](10)
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公开号
公开日
申请号
申请日
1.
US2014079783A1
2014/3/20
US201313935331
2013/7/3
专利标题
:Pharmaceutical Compositions Comprising Rifaximin and Amino acids, Preparation Methods and Use Thereof
专利权人
:
ALFA WASSERMANN SPA [IT]
;
The present invention relates to rifaximin compositions comprising amino acids, characterized in that they increase rifaximin solubility in aqueous solutions and are useful in the treatment of disease wherein amino acids and rifaximin are efficacious. The present invention also relates to pharmaceutical compositions comprising rifaximin or one of the pharmaceutically acceptable salts thereof and one or more amino acid(s), wherein the molar ratio between the amino acid(s) and rifaximin is from 1:...
2.
US2014065241A1
2014/3/6
US201314019207
2013/9/5
专利标题
:USES OF (-)-PERHEXILINE
专利权人
:
ADELAIDE RES & INNOVATION PTY [AU]
;
ITEK VENTURES PTY LTD [AU]
;
CENTRAL ADELAIDE LOCAL HEALTH NETWORK INC [AU]
;
A method for treating or preventing a disease, condition or state in a subject in need thereof by administering to the subject an effective amount of the (-)-enantiomer of perhexyline or a pharmaceutically acceptable salt, prodrug or derivative thereof, substantially free of the (+)-enantiomer, or pharmaceutical composition containing same. The disease, condition or state may be associated with altered tissue energetics, impaired tissue energetics, altered cardiac tissue energetics, impaired car...
3.
AU2012284010A1
2014/3/6
AU20120284010
2012/7/19
专利标题
:Targeted osmotic lysis of cancer cells
专利权人
:
UNIV LOUISIANA STATE
;
A targeted osmotic lysis (TOL) of tumor cells that over-express voltage-gated sodium channels (VGSCs) has been developed that uses a combined therapy of a drug that blocks sodium, potassium-adenosine triphosphatase (Na+, K+-ATPase) that is then followed by an activation of VGSCs, for example, by electrical or pharmacological stimulation. Activation of VGSCs conducts sodium into the cancer cells in much greater amounts than non-cancer cells. Water follows this sodium gradient into the cancer cell...
4.
WO2014031600A1
2014/2/27
WO2013US55724
2013/8/20
专利标题
:HAPTENS OF QUETIAPINE FOR USE IN IMMUNOASSAYS
专利权人
:
JANSSEN PHARMACEUTICA NV [BE]
;
ORTHO CLINICAL DIAGNOSTICS INC [US]
;
The invention relates to compounds of Formula I, wherein R1, R2, and R3 are defined in the specification, useful for the synthesis of novel conjugates and immunogens derived from quetiapine. The invention also relates to conjugates of a quetiapine hapten and a protein.
5.
US2014057298A1
2014/2/27
US201313971416
2013/8/20
专利标题
:Antibodies to Paliperidone and Use Thereof
专利权人
:
JANSSEN PHARMACEUTICA NV [BE]
;
ORTHO CLINICAL DIAGNOSTICS INC [US]
;
Disclosed is an antibody which binds to paliperidone, which can be used to detect paliperidone in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of paliperidone, including multiplex detection of aripiprazole, quetiapine, olanzapine, and risperidone/paliperidone in a single lateral flow assay device.
6.
US2014057297A1
2014/2/27
US201313971387
2013/8/20
专利标题
:Antibodies to Paliperidone Haptens and Use Thereof
专利权人
:
JANSSEN PHARMACEUTICA NV [BE]
;
ORTHO CLINICAL DIAGNOSTICS INC [US]
;
Disclosed is an antibody which binds to paliperidone, which can be used to detect paliperidone in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of paliperidone, including multiplex detection of aripiprazole, olanzapine, quetiapine, risperidone and paliperidone in a single lateral flow assay device.
7.
WO2014031595A1
2014/2/27
WO2013US55712
2013/8/20
专利标题
:HAPTENS OF PALIPERIDONE
专利权人
:
JANSSEN PHARMACEUTICA NV [BE]
;
ORTHO CLINICAL DIAGNOSTICS INC [US]
;
The invention relates to compounds of Formula (I), wherein L1, L2, and L3 are defined in the specification, useful for the synthesis of novel conjugates and immunogens derived from paliperidone. The invention also relates to conjugates of a paliperidone hapten and a protein.
8.
US2014057306A1
2014/2/27
US201313971562
2013/8/20
专利标题
:Antibodies to Quetiapine and Use Thereof
专利权人
:
JANSSEN PHARMACEUTICA NV [BE]
;
ORTHO CLINICAL DIAGNOSTICS INC [US]
;
Disclosed is an antibody which binds to quetiapine, which can be used to detect quetiapine in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of quetiapine, including multiplex detection of aripiprazole, quetiapine, olanzapine, and risperidone in a single lateral flow assay device.
9.
US2014057305A1
2014/2/27
US201313971546
2013/8/20
专利标题
:Antibodies to Quetiapine Haptens and Use Thereof
专利权人
:
JANSSEN PHARMACEUTICA NV [BE]
;
ORTHO CLINICAL DIAGNOSTICS INC [US]
;
Disclosed is an antibody which binds to quetiapine, which can be used to detect quetiapine in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of quetiapine, including multiplex detection of aripiprazole, olanzapine, quetiapine, and risperidone in a single lateral flow assay device.
10.
US2014057304A1
2014/2/27
US201313971536
2013/8/20
专利标题
:Antibodies to Olanzapine and Use Thereof
专利权人
:
JANSSEN PHARMACEUTICA NV [BE]
;
ORTHO CLINICAL DIAGNOSTICS INC [US]
;
Disclosed is an antibody which binds to olanzapine, which can be used to detect olanzapine in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of olanzapine, including multiplex detection of aripiprazole, olanzapine, quetiapine, and risperidone in a single lateral flow assay device.
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