There is provided a novel carbamoyloxy arylalkanoyl arylpiperazine derivative compound having abundant racemic or enantiomeric characteristics represented by the Formula 1 and pharmaceutically available salts or hydrates thereof. Also there are provided a pharmaceutical composition for treating pain anxiety or depression including an effective amount of the compound and a method for treating pain anxiety or depression in mammals by administering an effective amount of the compound to the mammals...

Crystalline anhydrous hydrochloride salts of 45?-epoxy-314-dihydroxy-17-methylmorphinan-6-one (oxymorphone) are disclosed and three polymorphic forms of these salts are reported. The invention further relates to a method for the production of such salts a pharmaceutical composition comprising an effective amount of such a salt and such a salt as a medicament and for the treatment and/or prevention of pain.

The invention relates to the preparation of phenolics derivatives by enzymatic condensation of phenolics selected among pyrocatechol or its derivatives with the glucose moiety of sucrose. The production of said phenolics derivatives is achieved with a glucosyltransferase (EC 2.4.1.5). These O-?-glucosides of selected phenolics are new have a solubility in water higher than that of their parent polyphenol and have useful applications in cosmetic and pharmaceutical compositions such as antioxidati...

The present invention relates to isolating phenolics from extra virgin olive oil (EVOO) having a low triglyceride and non-polar content. The method includes an ethanol/water extraction with a heptane wash

This invention provides a method of treating a patient afflicted with a neurodegenerative disorder e.g. Huntington's disease comprising administering to the patient rasagiline as an add-on therapy to or in combination with pridopidine. This invention also provides a package and a pharmaceutical composition comprising rasagiline and pridopidine for treating a patient afflicted with a neurodegenerative disorder. This invention also provides rasagiline for use as an add-on therapy or in combination...

This disclosure provides compositions containing solid forms of tazobactam arginine and methods of manufacturing and using these compositions.

The present invention provides compounds for the inhibition of soluble epoxide hydrolase and associated disease conditions.

A storage-stable dust-free homogeneous particulate formulation comprising at least one water-soluble Vitamin E-derivative and at least one hydrophilic polymer. In one embodiment the storage-stable dust-free homogeneous particle formulation consists of(j) at least one water-soluble Vitamin E-derivative(k) at least one hydrophilic polymer(l) optionally additional surface-active substances and(m) optionally additional pharmaceutical additiveswith the proviso that the sum of (a) (b) (c) and (d) equa...

The present invention provides a composition comprising a nicotine-containing material and an anti-cancer agent usable in the treatment and/or prevention or reduction of the risk of cancer and precancerous conditions as well as for preventing or reducing the risk of cancer recurrence. Furthermore a composition comprising a nicotine-containing material and an anti-inflammatory agent usable in the treatment and/or prevention or reduction of the risk of inflammation is provided. The nicotine contai...

Methods are provided for the synthesis of key intermediates for the synthesis of Argatroban monohydrate ethyl (2R4R)-1-[(2S)-2-amino-5-[[imino(nitroamino)methyl]amino]-1-oxopentyl]-4-methylpiperidine-2-carboxylate compounded with HCl. Such intermediates are also provided.