The invention relates to a method for manufacturing a polyoxyethylene alkyl ether acetic acid including feeding oxygen into a liquid phase containing polyoxyethylene ether having a hydrocarbon group at the end (hereinafter it may also be referred to as a polyoxyethylene alkyl ether) and water and dehydrogenating and oxidizing the polyoxyethylene alkyl ether in the presence of a platinum catalyst in which the mass ratio between the total mass of the polyoxyethylene alkyl ether and the polyoxyethy...

The present invention provides indane acetic acid and their derivatives and methods for the treating and/or preventing of Alzheimer's diseases.

The present invention provides a compound of formula I;

The present invention provides a mixed crystalline form VIII of agomelatine its method of preparation application and pharmaceutical composition. The said mixed crystal consists mainly of crystalline form VI of agomelatine. The said mixed crystalline form is stable and has good reproducibility. Through stability tests it has been found to be superior to the crystalline form VI in terms of stability. As a result the crystalline form VIII of the present invention possesses advantages in pharmaceut...

The invention discloses a method for the treatment of diseases particularly those diseases characterized by diminished or aberrant cellular function including AIDS cancer and Alzheimer's Disease. The method comprises administering a therapeutically effective amount of rosuvastatin enantiomer compounds in their (3R 5R) (3S 5R) or (3S 5S) configurations or pharmaceutically acceptable salts thereof. Biologically-active rosuvastatin enantiomer compounds with (3R 5R) (3S 5R) and (3S 5S) stereochemist...

A topical composition specifically an oil-in-water emulsion comprised of ketoprofen and oxybenzone in a physiologically acceptable topical carrier. The composition is applied topically to alleviate pain especially pain associated with migraine headache. The composition has good photostability as well as freeze/thaw stability.

The present invention is in the field of drug delivery and specifically cationic liposome-based drug delivery. In embodiments this invention provides methods of making ligand-targeted (e.g. antibody- or antibody fragment-targeted) liposomes useful for the delivery of liposomes to tumors including brain tumors. In embodiments the liposomes deliver temozolomide across the blood-brain barrier for treatment of primary or metastatic brain tumors. Additional cancers that can be treated with the liposo...