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专利详细信息
专利号
JP2012236853A
专利标题 Solid dosage form
专利权人 DAIICHI SANKYO CO LTD;
发明人
申请号 JP20120177601
申请日 2012/8/9
公开日 2012/12/6
优先权号
IPC A61K03144270;
专利类型
法律状态查询 查看法律状态


PROBLEM TO BE SOLVED: To provide a tablet containing an angiotensin II receptor antagonist and a calcium antagonist useful for treatment of hypertension and having an improved elution property. SOLUTION: The tablet is a nucleated tablet comprising granules containing olmesartan medoxomil as an active ingredient and granules containing amlodipine besilate or azelnidipine as another active ingredient wherein these granules are compounded in separate layers and the tablet further contains hydroxypropyl cellulose. Preferably the tablet contains olmesartan medoxomil in the inner core and amlodipine besilate or azelnidipine in the outer shell or contains amlodipine besylate or azelnidipine in the inner core and olmesartan medoxomil in the outer shell. COPYRIGHT: (C)2013JPO&INPIT
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