Pantoprazole sodium multiparticulates are described which avoid sticking to nasogastric and gastronomy tubes. The pantoprazole multiparticulates have a spheroid core of pantoprazole or an enantiomer thereof or a salt thereof a surfactant and a distintegrant; a sub coat which is comprised of hydroxypropyl methylcellulose (hypromellose) and water an enteric coat on the sub-coat and a final seal coat over the enteric coat which is composed of hydroxypropyl methylcellulose (hypromellose) and water.

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