专利详细信息
专利号 | US8133883B2 |
专利标题 | Compositions containing piperacillin and tazobactam useful for injection |
专利权人 | Pfizer Inc.; |
发明人 | Cohen, Jonathan M;Shah, Syed M;Ofslager, Christian L;Fawzi, Mahdi B; |
申请号 | US13/033861 |
申请日 | 2011/2/24 |
公开日 | 2012/3/13 |
优先权号 | |
IPC | A61K03170000; |
专利类型 | |
法律状态查询 | 查看法律状态 |
An aminocarboxylic acid chelating agent preferably EDTA or a salt thereof has been found to be useful for inhibiting particulate formation in piperacillin/tazobactam parenteral combinations. The composition may also contain a buffer preferably citrate and optionally an aminoglycoside. The product may be in the form of a frozen composition that can be thawed for use. The product may also be in the form of a cryodesiccated powder that can be reconstituted by addition of an aqueous vehicle to reform a solution.
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