PURPOSE: A composition containing a bivalent cation and anion pair is provided to prevent and/or treat diaper rash and atopic dermatitis. CONSTITUTION: A composition which prevents and/or treats enzymatic dermatitis contains a bivalent cation and anion pair and a carrier. The bivalent cation and anion pair is copper(II) chloride, copper(II) acetate, copper(II) gluconate, copper(II) lactate, zinc chloride, zinc acetate, zinc gluconate, zinc lactate, zinc carbonate, zinc borate, zinc aspartate, zinc pyrrolidone carboxylic acid, zinc citrate, iron(II) chloride, iron(II) acetate, iron(II) gluconate, calcium chloride, calcium acetate, calcium gluconate, calcium lactate, strontium chloride, strontium acetate, strontium gluconate, strontium lactate, magnesium chloride, magnesium acetate, magnesium gluconate, or magnesium lactate. A method for preventing and/or treating enzymatic dermatitis comprises a step of administering the composition. [Reference numerals] (AA) Trypsin inhibition activity(%)

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