专利详细信息
| 专利号 |
 |
| 专利标题 | Sorafenib dimethyl sulphoxide solvate |
| 专利权人 | RANBAXY LABORATORIES LIMITED; |
| 发明人 | Jaryal, Jagdev Singh;Sathyanarayana, Swargam;Thaper, Rajesh Kumar;Prasad, Mohan;Zade, Sachin Deorao;Singh, Ajay Shankar; |
| 申请号 | |
| 申请日 | |
| 公开日 | 2013/12/31 |
| 优先权号 | |
| IPC | A61K03144000; |
| 专利类型 | |
| 法律状态查询 | 查看法律状态 |
The present invention provides dimethyl sulphoxide solvate of 4-(4-{3-[4-chloro-3 -(trifluoromethyl)phenyl]ureido}phenoxy)-N2-methylpyridine-2-carboxamide process for its preparation pharmaceutical composition comprising it and its use for the treatment of cancer. The present invention also provides a novel HPLC method for the identification quantification and isolation of related substances of sorafenib.
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