专利详细信息
| 专利号 |
 |
| 专利标题 | Process for forming amorphous atorvastatin |
| 专利权人 | Pfizer Inc.; |
| 发明人 | Debettencourt, Iii Antone John;Shalaev, Evgenyi Yur Evich; |
| 申请号 | US11/666707 |
| 申请日 | 2005/10/12 |
| 公开日 | 2011/5/10 |
| 优先权号 | |
| IPC | C07D20741200; |
| 专利类型 | |
| 法律状态查询 | 查看法律状态 |
A process for forming amorphous atorvastatin comprising the steps of dissolving atorvastatin in a non-hydroxylic solvent and removing the solvent by freeze-drying as well as processes of dissolving atorvastatin in a hydroxylic solvent with a solubilizing agent or an alkalizing agent or an antioxidant and removing the solvent by freeze-drying to afford amorphous atorvastatin.
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