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专利详细信息
专利号
EP2481726A3
专利标题 Crystal forms of saxagliptin and processes for preparing same
专利权人 BRISTOL-MYERS SQUIBB COMPANY;
发明人 Gougoutas, Jack Z;Malley, Mary F;Dimarco, John D;Yin, Xiaotian S;Wei, Chenkou;Yu, Jurong;Vu, Truc Chi;Jones, Gregory Scott;Savage, Scott A;
申请号 EP20120164711
申请日 2008/4/18
公开日 2014/3/5
优先权号
IPC C07D20952000;
专利类型
法律状态查询 查看法律状态


Physical crystal structures of a compound of the formula (I): are provided including the free base monohydrate thereof (form H-1) and the hydrochloric acid salt thereof including hydrochloric acid salt containing 0.75 equivalent of H2O (form H0.75-3) and hydrochloric acid salt containing 2 equivalents of H2O (form H2-1) and hydrochloric acid salt Pattern P-5 preferably in substantially pure form and other forms as described herein pharmaceutical compositions containing structures of compound I or IA processes for preparing same intermediates used in preparing same and methods of treating diseases such as diabetes using such structures.
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