专利信息

首页 1 2 3 4 5 6 下页尾页共 1619 条记录, 当前第1/162页。

专利标题：Novel method for the synthesis of (7-methoxy-1-naphthyl)acetonitrile and application in the synthesis of agomelatine

专利权人：LES LABORATOIRES SERVIER;

专利标题：Delta crystalline form of the arginine salt of perindopril, a process for its preparation, and pharmaceutical compositions thereof

专利权人：LES LABORATOIRES SERVIER;

DELTA CRYSTALLINE FORM OF THE ARGININE SALT OF PERINDOPRIL A PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF Abstract Delta crystalline form of the compound of formula (I): : N CO~ I H 2 N NH H CHH3 H 3 (s) " NH 2 (s) CO2Et characterised by its X-ray powder diffraction diagram. Medicaments and methods of medical treatment are also disclosed.

专利标题：New crystalline form vi of agomelatine, preparation method and application thereof

专利权人：LES LABORATOIRES SERVIER;

A new crystalline form of Agomelatine its preparation method and application are provided. There are main peaks where diffraction angles 2 are 11.13� 11.82� 17.49� 18.29� 19.48� 19.72� 20.50� 21.76� 22.54� 22.97� 24.56� 25.36� 27.16� and 31.93� in the X-ray diffraction pattern of the crystalline form powder of Agomelatine. The new crystalline form has good purity stability and repeatability and has advantages in pharmaceutics. In addition the stability and solubility are better than those of cur...

专利标题：New crystalline form v of agomelatine, process for its preparation and pharmaceutical compositions containing it

专利权人：LES LABORATOIRES SERVIER;

专利标题：New process for the preparation of (2s,3as,7as)-1-[(s)-alanile]octahydro-1h-indole-2-carboxy acid derivatives and their use for synthesing perindopril

专利权人：LES LABORATOIRES SERVIER;

Process for industrial synthesis of (2S 3aS 7aS)-1-(S) alanyl octahydro-2-carboxylic acid derivatives (I) by reaction of alanine derivative (VI) and ester derivative (V) and catalytic hydrogenation. Process for industrial synthesis of (2S 3aS 7aS)-1-(S) alanyl octahydro-2-carboxylic acid derivatives of formula (I) comprises reaction of an ester of formula (V) with an alanine of formula (VI) in an organic solvent optionally in the presence of less than 0.6 mole per mole (V) of 1-hydroxybenzotri...

专利标题：Microcapsules for the delayed, controlled release of perindopril

专利权人：LES LABORATOIRES SERVIER;

The present invention relates to A microcapsule composition allowing the delayed and controlled release of perindopril or of a pharmaceutically acceptable salt thereof for administration by the oral route.

专利标题：Process for the synthesis of agomelatine

专利权人：LES LABORATOIRES SERVIER;

Process for the industrial synthesis of the compound of formula (I)

专利标题：Process for the synthesis of agomelatine

专利权人：LES LABORATOIRES SERVIER;

Process for the industrial synthesis of the compound of formula (I)

专利标题：New process for obtaining the crystalline form v of agomelatine

专利权人：LES LABORATOIRES SERVIER;

NEW PROCESS FOR OBTAINING THE CRYSTALLINE FORM V OF AGOMELATINE 5 Abstract The invention relates to a process for obtaining the crystalline form V of agomelatine of formula (1): NHCOMe MeO

专利标题：Novel method for synthesising perindopril and the pharmaceutically acceptable salt thereof

专利权人：LES LABORATOIRES SERVIER;

Preparation of perindopril (I) involves reacting 1-(1-cyclohexen-1-yl)-pyrrolidine (II) with a serine derivative (III); deprotecting the obtained cyclohexyl-serine derivative (IV) cyclizing and dehydrating; reacting the obtained hexahydroindole derivative (V) with N-((S)-1-ethoxycarbonyl-butyl)-(S)-alanine (VI); and hydrogenating and deprotecting the obtained hexahydroindole derivative (VII). Industrial production of (2S3aS7aS)-1-((2S)-2-((1S)-1-(ethoxycarbonyl)-butylamino)-propionyl)-octahydro...

当前查询条件: [专利权人组] 包含 '施维雅'

	查询范围	在当前结果中查询
!	专利类型	发明实用新型外观设计
!	公开号			CN1234
!	申请号			CN1234
!	专利标题		扩展	PHARMA
!	专利权人		扩展	pfizer
	发明人
!	申请日			yyyymmdd
!	公开日			yyyymmdd
	优先权号
!	摘要		扩展	PHARMA
	IPC			A01B

1. EP2176214B1	2014/3/5	EP20080842551	2008/8/1
专利标题：Novel method for the synthesis of (7-methoxy-1-naphthyl)acetonitrile and application in the synthesis of agomelatine 专利权人：LES LABORATOIRES SERVIER;

2. AU2012268815B2	2014/2/13
专利标题：Delta crystalline form of the arginine salt of perindopril, a process for its preparation, and pharmaceutical compositions thereof 专利权人：LES LABORATOIRES SERVIER; DELTA CRYSTALLINE FORM OF THE ARGININE SALT OF PERINDOPRIL A PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF Abstract Delta crystalline form of the compound of formula (I): : N CO~ I H 2 N NH H CHH3 H 3 (s) " NH 2 (s) CO2Et characterised by its X-ray powder diffraction diagram. Medicaments and methods of medical treatment are also disclosed.

3. EA019127B1	2014/1/30	EA20110001304	2010/3/9
专利标题：New crystalline form vi of agomelatine, preparation method and application thereof 专利权人：LES LABORATOIRES SERVIER; A new crystalline form of Agomelatine its preparation method and application are provided. There are main peaks where diffraction angles 2 are 11.13� 11.82� 17.49� 18.29� 19.48� 19.72� 20.50� 21.76� 22.54� 22.97� 24.56� 25.36� 27.16� and 31.93� in the X-ray diffraction pattern of the crystalline form powder of Agomelatine. The new crystalline form has good purity stability and repeatability and has advantages in pharmaceutics. In addition the stability and solubility are better than those of cur...

4. CA2555115C	2013/12/10	CA20062555115	2006/8/3
专利标题：New crystalline form v of agomelatine, process for its preparation and pharmaceutical compositions containing it 专利权人：LES LABORATOIRES SERVIER;

5. HU229396B1	2013/11/28	HU20020002437	2002/7/24
专利标题：New process for the preparation of (2s,3as,7as)-1-[(s)-alanile]octahydro-1h-indole-2-carboxy acid derivatives and their use for synthesing perindopril 专利权人：LES LABORATOIRES SERVIER; Process for industrial synthesis of (2S 3aS 7aS)-1-(S) alanyl octahydro-2-carboxylic acid derivatives (I) by reaction of alanine derivative (VI) and ester derivative (V) and catalytic hydrogenation. Process for industrial synthesis of (2S 3aS 7aS)-1-(S) alanyl octahydro-2-carboxylic acid derivatives of formula (I) comprises reaction of an ester of formula (V) with an alanine of formula (VI) in an organic solvent optionally in the presence of less than 0.6 mole per mole (V) of 1-hydroxybenzotri...

6. HRP20050055B1	2013/11/8	HR2005P000055	2005/1/19
专利标题：Microcapsules for the delayed, controlled release of perindopril 专利权人：LES LABORATOIRES SERVIER; The present invention relates to A microcapsule composition allowing the delayed and controlled release of perindopril or of a pharmaceutically acceptable salt thereof for administration by the oral route.

7. US20130289308A1	2013/10/31	US13/977796	2012/1/4
专利标题：Process for the synthesis of agomelatine 专利权人：LES LABORATOIRES SERVIER; Process for the industrial synthesis of the compound of formula (I)

8. US20130289307A1	2013/10/31	US13/977799	2012/1/4
专利标题：Process for the synthesis of agomelatine 专利权人：LES LABORATOIRES SERVIER; Process for the industrial synthesis of the compound of formula (I)

9. AU2009203071B2	2013/10/31	AU20090203071	2009/7/27
专利标题：New process for obtaining the crystalline form v of agomelatine 专利权人：LES LABORATOIRES SERVIER; NEW PROCESS FOR OBTAINING THE CRYSTALLINE FORM V OF AGOMELATINE 5 Abstract The invention relates to a process for obtaining the crystalline form V of agomelatine of formula (1): NHCOMe MeO

10. PL215131B1	2013/10/31	PL20040377238	2004/2/27
专利标题：Novel method for synthesising perindopril and the pharmaceutically acceptable salt thereof 专利权人：LES LABORATOIRES SERVIER; Preparation of perindopril (I) involves reacting 1-(1-cyclohexen-1-yl)-pyrrolidine (II) with a serine derivative (III); deprotecting the obtained cyclohexyl-serine derivative (IV) cyclizing and dehydrating; reacting the obtained hexahydroindole derivative (V) with N-((S)-1-ethoxycarbonyl-butyl)-(S)-alanine (VI); and hydrogenating and deprotecting the obtained hexahydroindole derivative (VII). Industrial production of (2S3aS7aS)-1-((2S)-2-((1S)-1-(ethoxycarbonyl)-butylamino)-propionyl)-octahydro...

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