Alkyl derivatives of trazodone of the formula (I) wherein only one of R R1 R2 and R3 is C1-3alkyl and the others are H and the acid addition salts thereof with physiologically acceptable organic or inorganic acids. These compounds exhibit pharmacological activity similar to those of trazodone but with reduced side effects. The invention also provides a process for preparing the compounds by reacting the general formula (I) compound with the general formula (III) compound wherein R R1 R2 and R3 a...

Alkylovderivy trazodonu obecno vzorce I ve kter pouze jeden ze substituentR R.sup.1.n. R.sup.2.n. nebo R.sup.3.n. pdstavuje C.sub.1.n.-C.sub.3.n. alkylovou skupinu a ostatnznamenajatom vodu a adisoli s fyziologicky pjatelni organicki nebo anorganicki kyselinami. Tyto slouniny projevujfarmakologickou innost. Je pops i zpob ppravy thto slounin reakcslouniny obecno vzorce II se slouninou obecno vzorce III kde R R.sup.1.n. R.sup.2.n. a R.sup.3.n. majshora uvedenvnym a X je boditelnskupina de mezipr...