A stable pharmaceutical composition comprising a mixture of (i) an ibuprofen medicament

A stable pharmaceutical composition comprising a mixture of (i) an ibuprofen medicament

The pharmaceutical composition contains ibuprofen or its salt from 200 to 3200 mg and domperidon or its salt from 10 to 100 mg and is used for the treatment of migraine.

The solid dosage medicamentous form is used for the treatment of pain and temperature running. It contains ibuprofen derivative and a carrier, including compressible filler, combined with disintegration ingredient. The ibuprofen derivative is 35% or more of the dosage form. The carrier also contains alcanometallic carbonate or bicarbonate in such a quantity that the dosage form shall have breaking strength of from 6.5 to 15 Kp and disintegration time no less than 10 min. 24 claims, 2 figures

FIELD: medicine, pharmacy. SUBSTANCE: invention relates to the ibuprofen composition that comprises phospholipid material mixed uniformly with medicinal agent ibuprofen. Medicinal agent ibuprofen is formed by an active component ibuprofen with melting point below 100 C. The mass ratio of phospho- lipid material and ibuprofen medicinal agent is from 0.02:1 to 0.2:1. In water addition indicated composition forms an aqueous-base preparation with pH value less 7. Preparation comprises an aqueous pha...

The invention relates to a pharmaceutical composition containing the sodium salt of S(-)ibuprofen as a dihydrate, and pharmaceutically acceptable carriers suitable for the administration as tablets, granules, capsules, liquid, gel, cataplasm, plaster or supository, being an anti-inflammatory, analgesic and anti-pyretic agent.

A compressed tablet composition comprising a granular component comprising a plurality of solidified melt granules of a non-steroidal non-inflammatory drug (NSAID) having a melting point in the range of 30-300 degrees C and incorporating a disintegrant uniformity dispersed therein

FIELD: medicine, pharmacy. SUBSTANCE: pharmaceutical composition for migraine treatment comprises therapeutically effective amounts of ibuprofen and domperidone or their pharmaceutically acceptable salts and pharmaceutically acceptable vehicle or carrier. Composition has no an antiacid agent. Invention claims method of migraine treatment involving administration of indicated composition. Patients suffering with migraine feel relief of migraine symptoms after simultaneous prescription of ibuprofe...

A pharmaceutical composition for the treatment of migraine or overindulgence comprising a therapeutically effective amount of racemic ibuprofen or a pharmaceutically acceptable salt or an enantiomer or a pharmaceutically acceptable salt thereof and a therapeutically effective amount of prochlorperazine or a pharmaceutically acceptable salt thereof.