It has been found that 12.5 mg ketoprofen is an effective analgesic and antipyretic. This low dosage is suitable for over-the-counter availability.

Onset-hastened and enhanced analgesic response is elicited in a mammalian organism in need of such treatment, i.e., a mammal suffering pain, by administering thereto a unit dosage onsethastening/enhancing analgesically effective amount of the S(+) ketoprofen enantiomer, said enantiomer being substantially free of its R(-) ketoprofen antipode.

The invention discloses an aqueous granulating solution containing sodium, potassium or mixed sodium potassium salt of an edible organic acid selected from the group consisting of citric, malic, tartaric and fumaric acid and optionally containing sodium or potassium bicarbonate. The granulating solution is especially useful for granulating finely divided solids including acetaminophen, ketoprofen or calcium carbonate. The resulting granulate may be used to prepare a swallow tablet or mixed with ...

Ultraviolet radiation induced erythema is prevented or treated in a human mammal in need of such prevention or treatment, i.e., a mammal suffering from or seeking to avoid sunburn, by topically administering thereto a unit dosage erythema-preventing or treating effective amount of the S(+) ketoprofen enantiomer, said enantiomer being substantially free of its R(-) ketoprofen antipode.

2093359 9205769 PCTABS00011 Ultraviolet radiation induced erythema is prevented or treated in a human mammal in need of such prevention or treatment, i.e., a mammal suffering from or seeking to avoid sunburn, by topically administering thereto a unit dosage erythema-preventing or treating effective amount of the S(+) ketoprofen enantiomer, said enantiomer being substantially free of its R(-) ketoprofen antipode.

An effervescent cold or sinus allergy medicine composition having reduced sodium content is produced from a mixture of an analgesic, such as acetylsalicylic acid, acetaminophen, ketoprofen, or a mixture thereof, citric acid, sodium bicarbonate, calcium carbonate, potassium bicarbonate, antihistamine, decongestant, and minor amounts of flavors and sweeteners. LED/ps MS-1586.1

An effervescent analgesic antacid composition having reduced sodium content is produced from a mixture of an analgesic, such as acetylsalicylic acid, acetaminophen, ketoprofen or a mixture thereof, citric acid, sodium bicarbonate, calcium carbonate, potassium bicarbonate, and minor amounts of flavors and sweeteners.