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XENOPORT INC [US](5)
GALLOP MARK A [US](5)
LI YUNXIAO [US](5)
JANDELEIT BERND [US](5)
ZERANGUE NOA [US](5)
VIRSIK PETER A [US](5)
FISCHER WOLF-NICOLAS [US](5)
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[专利权人] 包含 'FISCHER WOLF-NICOLAS [US]'
[药品] 包含 'Acamprosate'
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条记录, 当前第1/1页。
公开号
公开日
申请号
申请日
1.
WO2009052191A1
2009/4/23
WO2008US80009
2008/10/15
专利标题
:INTERNALLY MASKED NEOPENTYL SULFONYL ESTER CYCLIZATION RELEASE PRODRUGS OF ACAMPROSATE, COMPOSITIONS THEREOF, AND METHODS OF USE
专利权人
:
XENOPORT INC [US]
;
LI YUNXIAO [US]
;
JANDELEIT BERND [US]
;
GALLOP MARK A [US]
;
ZERANGUE NOA [US]
;
VIRSIK PETER A [US]
;
FISCHER WOLF-NICOLAS [US]
;
Internally masked neopentyl sulfonyl ester prodrugs of acamprosate, pharmaceutical compositions comprising such prodrugs, and methods of using such prodrugs and compositions thereof for treating diseases are disclosed. In particular, acamprosate prodrugs exhibiting enhanced oral bioavailability and methods of using acamprosate prodrugs to treat neurodegenerative disorders, psychotic disorders, mood disorders, anxiety disorders, somatoform disorders, movement disorders, substance abuse disorders,...
2.
WO2009033079A1
2009/3/12
WO2008US75472
2008/9/5
专利标题
:EXTERNALLY MASKED NEOPENTYL SULFONYL ESTER CYCLIZATION RELEASE PRODRUGS OF ACAMPROSATE, COMPOSITIONS THEREOF, AND METHODS OF USE
专利权人
:
XENOPORT INC [US]
;
JANDELEIT BERND [US]
;
LI YUNXIAO [US]
;
GALLOP MARK A [US]
;
ZERANGUE NOA [US]
;
VIRSIK PETER A [US]
;
FISCHER WOLF-NICOLAS [US]
;
Masked nitrogen-substituted and oxygen-substituted neopentyl sulfonyl ester prodrugs of acamprosate of formulae (I) and (III), pharmaceutical compositions comprising such prodrugs, and methods of using such prodrugs and compositions thereof for treating diseases are disclosed. In particular, acamprosate prodrugs exhibiting enhanced oral bioavailability and methods of using acamprosate prodrugs to treat neurodegenerative disorders, psychotic disorders, mood disorders, anxiety disorders, somatofor...
3.
WO2009033069A1
2009/3/12
WO2008US75462
2008/9/5
专利标题
:SIMPLE PANTOIC ACID ESTER NEOPENTYL SULFONYL ESTER CYCLIZATION RELEASE PRODRUGS OF ACAMPROSATE, COMPOSITIONS THEREOF, AND METHODS OF USE
专利权人
:
XENOPORT INC [US]
;
JANDELEIT BERND [US]
;
LI YUNXIAO [US]
;
GALLOP MARK A [US]
;
ZERANGUE NOA [US]
;
VIRSIK PETER A [US]
;
FISCHER WOLF-NICOLAS [US]
;
Pantoic acid ester neopentyl sulfonyl ester prodrugs of acamprosate of formula (I), pharmaceutical compositions comprising such prodrugs, and methods of using such prodrugs and compositions thereof for treating diseases are disclosed. In particular, acamprosate prodrugs exhibiting enhanced oral bioavailability and methods of using acamprosate prodrugs to treat neurodegenerative disorders, psychotic disorders, mood disorders, anxiety disorders, somatoform disorders, movement disorders, substance ...
4.
WO2009033061A1
2009/3/12
WO2008US75453
2008/9/5
专利标题
:MASKED CARBOXYLATE NEOPENTYL SULFONYL ESTER CYCLIZATION RELEASE PRODRUGS OF ACAMPROSATE, COMPOSITIONS THEREOF, AND METHODS OF USE
专利权人
:
XENOPORT INC [US]
;
JANDELEIT BERND [US]
;
LI YUNXIAO [US]
;
GALLOP MARK A [US]
;
ZERANGUE NOA [US]
;
VIRSIK PETER A [US]
;
FISCHER WOLF-NICOLAS [US]
;
Masked carboxylate neopentyl sulfonyl ester prodrugs of acamprosate of formula (I), pharmaceutical compositions comprising such prodrugs, and methods of using such prodrugs and compositions thereof for treating diseases are disclosed. In particular, acamprosate prodrugs exhibiting enhanced oral bioavailability and methods of using acamprosate prodrugs to treat neurodegenerative disorders, psychotic disorders, mood disorders, anxiety disorders, somatoform disorders, movement disorders, substance ...
5.
WO2009033054A1
2009/3/12
WO2008US75444
2008/9/5
专利标题
:COMPLEX PANTOIC ACID ESTER NEOPENTYL SULFONYL ESTER CYCLIZATION RELEASE PRODRUGS OF ACAMPROSATE, COMPOSITIONS THEREOF, AND METHODS OF USE
专利权人
:
XENOPORT INC [US]
;
JANDELEIT BERND [US]
;
LI YUNXIAO [US]
;
GALLOP MARK A [US]
;
ZERANGUE NOA [US]
;
VIRSIK PETER A [US]
;
FISCHER WOLF-NICOLAS [US]
;
Pantoic acid ester neopentyl sulfonyl ester prodrugs of acamprosate of formula (I), pharmaceutical compositions comprising such prodrugs, and methods of using such prodrugs and compositions thereof for treating diseases are disclosed. In particular, acamprosate prodrugs exhibiting enhanced oral bioavailability and methods of using acamprosate prodrugs to treat neurodegenerative disorders, psychotic disorders, mood disorders, anxiety disorders, somatoform disorders, movement disorders, substance ...
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