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SQUIBB BRISTOL MYERS CO [US](18)
ROBL JEFFREY A [US](5)
SULSKY RICHARD [US](3)
SULSKY RICHARD B [US](2)
HARVARD COLLEGE [US](1)
CAULFIELD THOMAS J [FR](1)
PARKER REX A [US](1)
MAGNIN DAVID R [US](1)
专利信息
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[专利权人] 包含 'SQUIBB BRISTOL MYERS CO [US]'
[药品] 包含 'Troglitazone'
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条记录, 当前第1/2页。
公开号
公开日
申请号
申请日
1.
US7390824B1
2008/6/24
US19990391053
1999/9/7
专利标题
:Method for treating diabetes employing an aP2 inhibitor and combination
专利权人
:
SQUIBB BRISTOL MYERS CO [US]
;
HARVARD COLLEGE [US]
;
A method is provided for treating diabetes and related diseases, especially Type II diabetes, employing an aP2 inhibitor or a combination of an aP2 inhibitor and another antidiabetic agent such as metformin, glyburide, troglitazone and/or insulin.
2.
KR20060026125A
2006/3/22
KR20067004515
2006/3/3
专利标题
:CYCLOPROPYL-FUSED PYRROLIDINE-BASED INHIBITORS OF DIPEPTIDYL IV, PROCESSES FOR THEIR PREPARATION, AND THEIR USE
专利权人
:
SQUIBB BRISTOL MYERS CO [US]
;
Dipeptidyl peptidase IV (DP 4) inhibiting compounds are provided having the formula (I) where x is 0 or 1 and y is 0 or 1 (provided that x = 1 when y = 0 and x = 0 when y = 1)
3.
EP1559710A2
2005/8/3
EP20050005368
2001/3/5
专利标题
:Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV, process for their preparation and their use
专利权人
:
SQUIBB BRISTOL MYERS CO [US]
;
Dipeptidyl peptidase IV (DP 4) inhibiting compounds are provided having the formula (I) where x is 0 or 1 and y is 0 or 1 (provided that x = 1 when y = 0 and x = 0 when y = 1)
4.
WO03043624A1
2003/5/30
WO2002US36580
2002/11/15
专利标题
:DUAL INHIBITORS OF ADIPOCYTE FATTY ACID BINDING PROTEIN AND KERATINOCYTE FATTY ACID BINDING PROTEIN
专利权人
:
SQUIBB BRISTOL MYERS CO [US]
;
MAGNIN DAVID R [US]
;
SULSKY RICHARD B [US]
;
ROBL JEFFREY A [US]
;
CAULFIELD THOMAS J [FR]
;
PARKER REX A [US]
;
Compounds that are dual aP2/k-FABP inhibitors are provided having the formula (I), wherein A, B, X, Y, R<1>, R<2> and R<3> are as described herein. A method is also provided for treating diabetes and related diseases, especially Type II diabetes, employing dual aP2/k-FABP inhibitors alone or in combination with at least one other antidiabetic agent such as metformin, glyburide, troglitazone and/or insulin.
5.
US6548529B1
2003/4/15
US20000519079
2000/3/6
专利标题
:Heterocyclic containing biphenyl aP2 inhibitors and method
专利权人
:
SQUIBB BRISTOL MYERS CO [US]
;
aP2 inhibiting compounds are provided having the formulawherein R1, R2, R3, R4, X-Z andare as described herein.A method is also provided for treating diabetes and related diseases, especially Type II diabetes, employing such aP2 inhibitor or a combination of such aP2 inhibitor and another antidiabetic agent such as metformin, glyburide, troglitazone and/or insulin.
6.
WO03006023A1
2003/1/23
WO2002US22186
2002/7/12
专利标题
:PYRAZINONE INHIBITORS OF FATTY ACID BINDING PROTEIN AND METHOD
专利权人
:
SQUIBB BRISTOL MYERS CO [US]
;
SULSKY RICHARD [US]
;
ROBL JEFFREY A [US]
;
aP2 inhibiting compounds are provided having the formula [I] wherein A, X, R and Z are as described herein. A method is also provided for treating diabetes and related diseases, especially Type II diabetes, employing such aP2 inhibitors alone or in combination with other therapeutic agents, including other antidiabetic agent such as metformin, glyburide, troglitazone and/or insulin.
7.
WO02083128A1
2002/10/24
WO2002US10936
2002/4/5
专利标题
:2,1-OXAZOLINE AND 1,2-PYRAZOLINE-BASED INHIBITORS OF DIPEPTIDYL PEPTIDASE IV AND METHOD
专利权人
:
SQUIBB BRISTOL MYERS CO [US]
;
SULSKY RICHARD B [US]
;
ROBL JEFFREY A [US]
;
Dipeptidyl peptidase IV (DP 4) inhibiting compounds are provided having the formula where n is 0 or 1
8.
CA2444465A1
2002/10/24
CA20022444465
2002/4/5
专利标题
:2,1-OXAZOLINE AND 1,2-PYRAZOLINE-BASED INHIBITORS OF DIPEPTIDYL PEPTIDASE IV AND METHOD
专利权人
:
SQUIBB BRISTOL MYERS CO [US]
;
Dipeptidyl peptidase IV (DP 4) inhibiting compounds are provided having the formula where n is 0 or 1
9.
WO0240448A1
2002/5/23
WO2001US43647
2001/11/20
专利标题
:PYRIDONE DERIVATIVES AS AP2 INHIBITORS
专利权人
:
SQUIBB BRISTOL MYERS CO [US]
;
SULSKY RICHARD [US]
;
ROBL JEFFREY A [US]
;
aP2 inhibiting compounds are provided having the formula wherein A, Q, and X are as described herein. A method is also provided for treating diabetes and related diseases, especially Type II diabetes, employing such aP2 inhibitor or a combination of such aP2 inhibitor and another antidiabetic agent such as metformin, glyburide, troglitazone and/or insulin.
10.
CA2436854A1
2002/5/23
CA20012436854
2001/11/20
专利标题
:PYRIDONE DERIVATIVES AS AP2 INHIBITORS
专利权人
:
SQUIBB BRISTOL MYERS CO [US]
;
aP2 inhibiting compounds are provided having the formula wherein A, Q, and X are as described herein. A method is also provided for treating diabetes and related diseases, especially Type II diabetes, employing such aP2 inhibitor or a combination of such aP2 inhibitor and another antidiabetic agent such as metformin, glyburide, troglitazone and/or insulin.
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