PROBLEM TO BE SOLVED: To obtain the subject composition capable of improving the adhesive strength of sucralfate to a neutral mucosal upper stratal site in an anorectal region, in the vagina or in the urethra, promoting the persistence of protecting and therapeutic effects of an affected part and achieving the enhancement of healing effects by formulating sucralfate in a high ratio. SOLUTION: This composition contains (A) 50-80 wt.% of sucralfate, (B) a pH adjustor (e.g. disodium citrate) in an ...

PROBLEM TO BE SOLVED: To obtain the subject composition useful as a gastrointestinal medicine in which sucralfate sufficiently can adhere to mucosa in reaching a stomach, sustain the antiacid action of a gastric antiacid for many hours after the adhesion and raise antitumor actions, by including sucralfate and a coated gastric antiacid. SOLUTION: This composition comprises (A) sucralfate and (B) a coated gastric antiacid preferably in an amount of 500-1,080 mg of the component A and 500-1,400-mg...