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CHUGAI PHARMACEUTICAL CO LTD [JP](43)
OZAWA KOICHI [JP](3)
SATO PHARMA [JP](2)
IGUSA KAZUO [JP](2)
YAMAZAKI TAMOTSU [JP](2)
FUJI CHEM IND CO LTD [JP](1)
IKUSHIMA HEIJI [JP](1)
SHIRAI TETSUO [JP](1)
SHINKAI CHIE [JP](1)
HIGO SHOICHI [JP](1)
专利信息
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[专利权人] 包含 'CHUGAI PHARMACEUTICAL CO LTD [JP]'
[药品] 包含 'Sucralfate'
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公开号
公开日
申请号
申请日
1.
US6555137B1
2003/4/29
US19990446871
1999/12/29
专利标题
:Sucralfate-containing composition and process for the preparation thereof
专利权人
:
CHUGAI PHARMACEUTICAL CO LTD [JP]
;
FUJI CHEM IND CO LTD [JP]
;
A coated antacid comprising sucralfate and an antacid inhibits decline in the adhesion characteristics of sucralfate whereby the drug ingested can reliably show its effect in the stomach. This coated antacid not only shows the mucosa repairing effect of sucralfate itself, but also shows the antacid effect and the gastric mucosa protective effect of the coated antacid, thereby synergistically producing an excellent antiulcer effect and an excellent ulcer inhibiting/healing effect.
2.
EP1110540A1
2001/6/27
EP20010105293
1995/4/18
专利标题
:Melt granulated sucralfate preparations
专利权人
:
CHUGAI PHARMACEUTICAL CO LTD [JP]
;
Sucralfate preparation produced by melt granulating a mixture of a comminuted sucralfate powder and a water-soluble low-melting point wax, as well as a process for producing a sucralfate preparation comprising the steps of comminuting dry sucralfate into fine particles, mixing the finely divided particles with a water-soluble low-melting point wax and heating the mixture such that the wax is melted to effect melt (adhesion) granulation of the finely divided sucralfate particles are disclosed. Co...
3.
EP1074259A1
2001/2/7
EP19990910696
1999/3/25
专利标题
:PREVENTIVES FOR ALCOHOLIC GASTRITIS
专利权人
:
CHUGAI PHARMACEUTICAL CO LTD [JP]
;
A prophylactic drug for the prevention of acute alcoholic gastritis, comprising a combination of sucralfate and a histamine H2-receptor antagonist, particularly preferably famotidine, is disclosed. This prophylactic drug shows a marked synergistic action in preventing acute alcoholic gastritis, in comparison with each of the constituent drugs being used alone. The combined use of the two drugs enables a marked reduction in the respective necessary doses.
4.
KR100264547B1
2000/12/1
KR19967005975
1996/10/24
专利标题
:MOLTEN GRANULATED SUCRALFATE PREPARATION AND PROCESS FOR PRODUCING THE SAME
专利权人
:
CHUGAI PHARMACEUTICAL CO LTD [JP]
;
A sucralfate preparation prepared by melt granulating a mixture of a sucralfate powder with a water-soluble low-melting wax;and a process for producing a sucralfate preparation by atomizing dry sucralfate, adding a water-soluble low-melting wax to the atomized powder, and heat melting the wax to effect melt (fusion) granulation of the atomized sucralfate. As compared with conventional sucralfate preparations, the above preparation is reduced in the size of dispersed particles, has a high ability...
5.
EP1000614A1
2000/5/17
EP19980924612
1998/6/15
专利标题
:SUCRALFATE-CONTAINING COMPOSITION AND PROCESS FOR THE PREPARATION THEREOF
专利权人
:
CHUGAI PHARMACEUTICAL CO LTD [JP]
;
A coated antacid which is used for concoctions of sucralfate with an antacid, prevents the adhering characteristics of sucralfate from lowering, and permitting the administered drug to exhibit its activities in the stomach without fail. Specifically, a gastrointestinal drug which is enhanced in the solubility of sucralfate in the stomach by inhibiting the reaction of an antacid with gastric hydrochloric acid in an early stage of arrival at the stomach to thereby make sucralfate exhibit a suffici...
6.
EP0974361A1
2000/1/26
EP19970902609
1997/2/7
专利标题
:METHOD OF USING ANTACID AGENT AND PHARMACEUTICAL PREPARATION CONTAINING ANTACID AGENT
专利权人
:
CHUGAI PHARMACEUTICAL CO LTD [JP]
;
A method of using an antacid for preventing sucralfate from adsorbing or trapping another drug, as well as a pharmaceutical preparation comprising sucralfate, another drug and an antacid such that the another drug is prevented from being adsorbed on or trapped by sucralfate are disclosed. The use of the antacid in an environment where sucralfate is used along with another drug can prevent the occurrence of interactions between sucralfate and the another drug such as inhibited or delayed absorpti...
7.
US5985843A
1999/11/16
US19970930263
1997/9/26
专利标题
:Pharmaceutical composition containing sucralfate
专利权人
:
CHUGAI PHARMACEUTICAL CO LTD [JP]
;
PCT No. PCT/JP96/00891 Sec. 371 Date Sep. 26, 1997 Sec. 102(e) Date Sep. 26, 1997 PCT Filed Apr. 2, 1996 PCT Pub. No. WO96/31218 PCT Pub. Date Oct. 10, 1996Disclosed is a pharmaceutical preparation that contains sucralfate is the presence of another drug and which consists of a delayed release fraction of sucralfate and an immediate release fraction of the another drug. The preparation exhibits an outstanding feature such that when administered, the drug coexistent with the sucralfate can mainta...
8.
US5968906A
1999/10/19
US19970875748
1997/8/4
专利标题
:Sucralfate preparations
专利权人
:
CHUGAI PHARMACEUTICAL CO LTD [JP]
;
PCT No. PCT/JP96/00217 Sec. 371 Date Aug. 4, 1997 Sec. 102(e) Date Aug. 4, 1997 PCT Filed Feb. 2, 1996 PCT Pub. No. WO96/23507 PCT Pub. Date Aug. 8, 1996Sucralfate containing preparations which contain both an organic acid having at least two carboxyl groups or at least one carboxyl group in the molecule and sucralfate are described. The sucralfate containing preparations have enhanced sucralfate adhesion to the mucosal ulcer site even under a nonacidic condition and can be extensively applied n...
9.
WO9949872A1
1999/10/7
WO1999JP01509
1999/3/25
专利标题
:PREVENTIVES FOR ALCOHOLIC GASTRITIS
专利权人
:
CHUGAI PHARMACEUTICAL CO LTD [JP]
;
IGUSA KAZUO [JP]
;
YAMAZAKI TAMOTSU [JP]
;
Preventives for acute alcoholic gastritis containing a combination of sucralfate with histamine H2 receptor antagonists, preferably famotidine. Compared with the case where each active ingredient is used alone, the above drugs show remarkable synergistic effects of preventing acute alcoholic gastritis. The combined use of these two ingredients makes it possible to considerably reduce the administration dose.
10.
CA2320421A1
1999/10/7
CA19992320421
1999/3/25
专利标题
:PROPHYLACTIC DRUG FOR PREVENTION OF ALCOHOLIC GASTRITIS
专利权人
:
CHUGAI PHARMACEUTICAL CO LTD [JP]
;
Preventives for acute alcoholic gastritis containing a combination of sucralfate with histamine H2 receptor antagonists, preferably famotidine. Compared with the case where each active ingredient is used alone, the above drugs show remarkable synergistic effects of preventing acute alcoholic gastritis. The combined use of these two ingredients makes it possible to considerably reduce the administration dose.
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