The invention relates to new pharmaceutical compositions inhibiting gastric acid secretion and exerting gastrocytoprotective effect which contain as active ingredient a 10:1-1:10 (w/w) mixture of a compound of general formula (II), wherein X represents an oxygen or sulfur atom, and R represents a hydrogen atom, a hydroxy, C1-4 alkyl or C1-4 alkoxy group, or a compound of general formula (III), wherein R<1> represents a hydrogen or halogen atom, and a compound of general formula (IV), or a compou...

Prepn. of the A modification of cimetidine (I-A

A b s t r a c t The invention relates to new anti-ulcer or anti-ulcer and antiinflammatory compositions, which contain a combination of an anti-ulcer agent or a salt thereof with salicylic acid or an alkali metal salt thereof and optionally a non-steroidal antiinflammatory agent or a salt thereof. As an anti-ulcer agent preferably cimetidine or ranitidine is employed, while the preferred non-steroidal antiinflammatory agent is indomethacin. The new compositions according to the invention are dev...