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LEK TOVARNA FARMACEVTSKIH [YU](10)
专利信息
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[专利权人] 包含 'LEK TOVARNA FARMACEVTSKIH [YU]'
[药品] 包含 'Cimetidine'
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公开号
公开日
申请号
申请日
1.
CA1333156C
1994/11/22
CA19890603116
1989/6/16
专利标题
:DISPERSIBLE CIMETIDINE TABLETS
专利权人
:
LEK TOVARNA FARMACEVTSKIH [YU]
;
There are described novel dispersible cimetidine tablets containing 30 to 90 % by weight of one of the polymorphous modifications of cimetidine A, B or C, 5 to 55 % by weight of one or more disintegrationg agents, 0.05 to 5.0 % by weight of a surfactant, such as sodium lauryl sulphate together with other common adjuvants. The process for the manufacture of dispersible cimetidine tablets is effected on the basis of known methods by granulating the ingredients and by compressing the granu-late to ...
2.
US5069910A
1991/12/3
US19890366437
1989/6/15
专利标题
:DISPERSIBLE CIMETIDINE TABLETS
专利权人
:
LEK TOVARNA FARMACEVTSKIH [YU]
;
3.
YU136789A
1991/2/28
YU19890001367
1989/7/10
专利标题
:PROCESS FOR PREPARING CIMETIDINE
专利权人
:
LEK TOVARNA FARMACEVTSKIH [YU]
;
4.
YU120988A
1990/6/30
YU19880001209
1988/6/23
专利标题
:PROCESS FOR PREPARING NEW DISPERSION PILLS OF CIMETIDINE
专利权人
:
LEK TOVARNA FARMACEVTSKIH [YU]
;
5.
EP0347767A1
1989/12/27
EP19890110951
1989/6/16
专利标题
:Dispersible cimetidine tablets.
专利权人
:
LEK TOVARNA FARMACEVTSKIH [YU]
;
There are described novel dispersible cimetidine tablets containing 30 to 90 % by weight of one of the polymorphous modifications of cimetidine A, B or C, 5 to 55 % by weight of one or more disintegrationg agents, 0.05 to 5.0 % by weight of a surfactant, such as sodium lauryl sulphate together with other common adjuvants. The process for the manufacture of dispersible cimetidine tablets is effected on the basis of known methods by granulating the ingredients and by compressing the granulate to t...
6.
US4855439A
1989/8/8
US19880147423
1988/1/25
专利标题
:Process for the preparation of cimetidine
专利权人
:
LEK TOVARNA FARMACEVTSKIH [YU]
;
A new and simple process for the preparation of crystalline cimetidine (N-cyano-N'-methyl-N''-{2/(5-methyl-1H-imidazole-4-yl)methylthio/ethyl}gu anidine) is described wherein cimetidine is obtained by reacting O-ethyl-S-(4-methylimidazolyl-5-methyl)dithiocarbonate hydrobromide with N-cyano-N'-methyl-N''-(2-chloroethyl)guanidine in an aqueous methylamine solution at a temperature between room temperature and the reflux temperature of the reaction mixture, whereupon the desired compound is separat...
7.
YU9187A
1988/12/31
YU19870000091
1987/1/23
专利标题
:PROCESS FOR PREPARING CIMETIDINE
专利权人
:
LEK TOVARNA FARMACEVTSKIH [YU]
;
8.
YU219586A
1988/10/31
YU19860002195
1986/12/19
专利标题
:PROCESS FOR PREPARING CRYSTALLINE CIMETIDINE
专利权人
:
LEK TOVARNA FARMACEVTSKIH [YU]
;
9.
US4720552A
1988/1/19
US19870043125
1987/4/27
专利标题
:Process for the preparation of acid addition salts of 4(5)-methyl-5(4)-thiomethyl imidazole
专利权人
:
LEK TOVARNA FARMACEVTSKIH [YU]
;
A new, technologically easily feasible process for the preparation of 4(5)-methyl-5(4)-thiomethyl imidazole of the formula
and of acid addition salts thereof is described, wherein 4(5)-methyl-5(4)-bromomethyl imidazole hydrobromide is reacted in an aqueous medium at room temperature with potassium O-ethyl dithiocarbonate to the intermediate O-ethyl-S-(4-methylimidazolyl-5-methyl) dithiocarbonate, which is hydrolyzed at the reflux temperature under nitrogen atmosphere with an aqueous HBr ...
10.
YU168981A
1984/2/29
YU19810001689
1981/7/8
专利标题
:PROESS FOR PRODUCING CIMETIDINE
专利权人
:
LEK TOVARNA FARMACEVTSKIH [YU]
;
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