The present invention comprises a bi-layer, pharmaceutical tablet having one layer formulated for the immediate release (IR) of ranitidine and a second layer formulated for sustained release (SR) of ranitidine with the ratio of ranitidine in the IR layer to that in the SR in the range of from about 30:70 to about 60:40.

A pharmaceutical composition for gastrointestinal conditions comprising ranitidine and calcium carbonate.

This invention relates to an improved polymeric film coating for a ranitidine hydrochloride (HCl) tablet in which the plasticizer triacetin has been added to the polymeric film coating medium. A tablet of this invention has been found to have greater stability than a tablet coating with a polymeric film which does not contain triacetin.