The present invention comprises a bi-layer, pharmaceutical tablet having one layer formulated for the immediate release (IR) of ranitidine and a second layer formulated for sustained release (SR) of ranitidine with the ratio of ranitidine in the IR layer to that in the SR in the range of from about 30:70 to about 60:40.

This invention relates to an improved polymeric film coating for a ranitidine Hydrocholride (HCl) tablet in which the plasticizer triacetin had been added to the polymeric film coating medium. A tablet of this invention has been found to have great stability than a tablet coating with a polymeric film which does not contain triacetin.

lt;Pgt;L'invention a trait aux comprimés de chlorhydrate de ranitidine enrobés.lt;/Pgt;lt;Pgt;Elle a pour objet un revêtement de film polymère amélioré pour un comprimé de chlorhydrate de ranitidine dans lequel le plastifiant triacétine a été ajouté au milieu d'enrobage par film polymère.lt;/Pgt;lt;Pgt;On a trouvé qu'un comprimé selon l'invention a une plus grande stabilité qu'un comprimé revêtu d'un film polymère qui ne contient pas de triacétine.lt;/Pgt;