A unit dosage form such as a capsule or the like for delivering drugs into the body in a sustained release fashion similar to that produced by INDERAL® LA indicated for the treatment of cardiovascular diseases comprises two populations of propranolol-containing particles (beads pellets granules etc.). Each bead population exhibits a pre-designed rapid release profile (i.e. substantially complete release within 60 minutes) or sustained release profile over a period of 24 hours. Such a cardiovascu...

A unit dosage form such as a capsule or the like for delivering drugs into the body in a circadian release fashion is comprising of one or more populations of propranolol-containing particles (beads pellets granules etc.). Each bead population exhibits a pre-designed rapid or sustained release profile with or without a predetermined lag time of 3 to 5 hours. Such a circadian rhythm release cardiovascular drug delivery system is designed to provide a plasma concentration-time profile which varies...

A unit dosage form such as a capsule or the like for delivering drugs into the body in a sustained release fashion similar to that produced by INDERAL LA indicated for the treatment of cardiovascular diseases comprises two populations of propranolol-containing particles (beads pellets granules etc.). Each bead population exhibits a pre-designed rapid release profile (i.e. substantially complete release within 60 minutes) or sustained release profile over a period of 24 hours. Such a cardiovascul...

A unit dosage form such as a capsule or the like for delivering drugs into the body in a circadian release fashion is comprising of one or more populations of propranolol-containing particles (beads pellets granules etc.). Each bead population exhibits a pre-designed rapid or sustained release profile with or without a predetermined lag time of 3 to 5 hours. Such a circadian rhythm release cardiovascular drug delivery system is designed to provide a plasma concentrationtime profile which varies ...

A unit dosage form such as a capsule or the like for delivering drugs into the body in a circadian release fashion is comprising of one or more populations of propranolol-containing particles (beads pellets granules etc.). Each bead population exhibits a pre-designed rapid or sustained release profile with or without a predetermined lag time of 3 to 5 hours. Such a circadian rhythm release cardiovascular drug delivery system is designed to provide a plasma concentrationtime profile which varies ...