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  • [专利权人] 包含 'ASTRA AB'
  • [药品] 包含 'Metoprolol '
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标题标题2专利权人发明人附图摘要摘要2优先权号IPC专利类型
首页1尾页9 条记录, 当前第1/1页。
公开号 公开日 申请号 申请日
1. IN187175A1 2002/2/23 IN1997DE03275 1997/11/13
专利标题:A method for the manufacture of metoprolol 法律状态
专利权人ASTRA AB;


2. NZ335213A 2001/2/23 NZ19960335213 1996/11/18
专利标题:Metoprolol and a method of preparing metoprolol by reacting p-(2-methoxyethyl)phenol and epichlorohydrin and isopropylamine 法律状态
专利权人ASTRA AB;


3. AU728270B2 2001/1/4 AU19980050776 1997/11/18
专利标题:New manufacturing process of metoprolol 法律状态
专利权人ASTRA AB;


4. KR20000057134A 2000/9/15 KR19997004401 1999/5/19
专利标题:NEW MANUFACTURING PROCESS OF METOPROLOL 法律状态
专利权人ASTRA AB;
PURPOSE: An improved method for the manufacture of metoprolol base that uses no other solvents than water for the reaction of p-(2-methoxyethyl)phenol and epichlorohydrin is provided. The method is environmentally sound and gives a good yield and high purity. CONSTITUTION: A method for the manufacture of metoprolol comprises : (i) reacting in a first step p-(2-methoxyethyl)phenol and epichlorohydrin in water as solvent and at a temperature of 50 to 700[deg.]C, evaporating the excess of epichloro...


5. NO992401A 1999/7/13
专利标题:Ny fremgangsmÕte for fremstilling av metoprolol 法律状态
专利权人ASTRA AB;


6. NO992401D0 1999/5/19
专利标题:Ny fremgangsmÕte for fremstilling av metoprolol 法律状态
专利权人ASTRA AB;


7. AU5077698A 1998/6/10 AU19980050776D 1997/11/18
专利标题:New manufacturing process of metoprolol 法律状态
专利权人ASTRA AB;


8. ZA9710005A 1998/5/20 ZA19970010005 1997/11/6
专利标题:New manufacturing process of metoprolol. 法律状态
专利权人ASTRA AB;


9. SE9604253D0 1996/11/20
专利标题:New manufacturing process metoprolol 法律状态
专利权人ASTRA AB;
A method for the manufacture of metoprolol wherein the process is performed in water as solvent.



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