PROBLEM TO BE SOLVED: To obtain a preparation adhering to mucous membrane of oral cavity which has good moldability stably adheres to oral mucosa for hours and can gradually release medicines.SOLUTION: This preparation contains 25-75% of gellant gum as a natural product. In addition at least one selected from pectin chitosan or hydroxypropylcellulose is admixed. Further proper excipient and a medicine are admixed and the mixture is directly compressed with a pelletizer to give the objective prep...

PURPOSE: To obtain the titled pharmaceutical useful as a remedy for angina pectoris by incorporating and copulverizing a copulverized fine powdery composition obtained from a salt e.g. magnesium silicate or Mg(sub 2)CO(sub 3) etc. with casein and nifedipine with an enteric coating agent and a plasticizer and dry granulating the resultant mixture.CONSTITUTION: One or more selected from magnesium silicate Mg(sub 2)CO(sub 3) dried aluminum hydroxide gel etc. are copulverized with casein and nifedip...

PURPOSE: The titled pharmaceutical preparation having extremely improved dissolution properties useful for remedying angina pectoris or hypertension obtained by blending nifedipine with a specific compound and casein crushing them in a mixed state.CONSTITUTION: The titled pharmaceutical preparation containing ultrafine composition obtained by blending one or more selected from a group consisting of magnesium silicate magnesium carbonate dried aluminum hydroxide gel magnesium oxide magnesium meta...

PURPOSE: To obtain the titled pharmaceutical useful as a remedy for angina pectoris by incorporating and copulverizing a copulverized fine powdery composition obtained from a salt e.g. magnesium silicate or Mg(sub 2)CO(sub 3) etc. with casein and nifedipine with an enteric coating agent and a plasticizer and dry granulating the resultant mixture.CONSTITUTION: One or more selected from magnesium silicate Mg(sub 2)CO(sub 3) dried aluminum hydroxide gel etc. are copulverized with casein and nifedip...

lt;Pgt;L'INVENTION CONCERNE UNE NOUVELLE PREPARATION SOLIDE DE NIFEDIPINE ET SA FABRICATION.lt;/Pgt;lt;Pgt;LA PREPARATION SELON L'INVENTION CONSISTE EN UNE COMPOSITION SECHE EN PARTICULES QUI A ETE OBTENUE EN SOUMETTANT LA NIFEDIPINE A LA COPULVERISATION EN MELANGE AVEC LA CASEINE ET UN OU PLUSIEURS EXCIPIENTS INORGANIQUE.lt;/Pgt;lt;Pgt;APPLICATIONS DISSOLUTION PROGRESSIVE DE LA NIFEDIPINE ET MAINTIEN DE CONCENTRATIONS ELEVEES DANS LE PLASMA PENDANT UNE LONGUE DUREE.lt;/Pgt;