PURPOSE: To prepare the subject drug preparation having excellent oral absorptivity of nifedipine and sustainability of the concentration in blood plasma and exhibiting sufficient prevention and treatment effect on stenocardia and hypertension at a small number of administration doses.CONSTITUTION: This nifedipine-containing sustained action drug is produced by coating a core particle with a solid dispersion composition composed of (A) nifedipine and (B) a base selected from a water-soluble cell...

PURPOSE: To prepare the titled pharmaceutical preparation useful for remedying breast pang obtained by coating a fine particle carrier made of a water-soluble drug additive with a solid solution of nifedipine and hydroxypropylmethyl cellulose or methyl cellulose.CONSTITUTION: A water-soluble drug additive (e.g. lactose white sugar glucose) is blended with an aqueous solution of a binder (e.g. hydroxypropyl cellulose gelatin) and granulated to give a fine particle carrier which is coated with a s...

PURPOSE: To prepare the titled preparation having high water-solubility and excellent uniformity by coating fine granules obtained by the granulation of a water-soluble pharmaceutical additive with a solid solution consisting of nifedipine which is a hardly water-soluble remedy for stenocardia and polyvinyl pyrrolidone.CONSTITUTION: A water-soluble pharmaceutical additive (e.g. a water-soluble vehicle such as lactose glucose etc. a diluent a binder a surface-active agnet etc.) is granulated to f...

PURPOSE: To provide an easily absorbable nifedipine composition and an antistenocardia containing said composition composed of a polyethylene glycol solution of nifedipine infiltrated into a porous material.CONSTITUTION: Nifedipine[14-dihydro-26-dimethyl-4-(2-nitrophenyl)-35-pyridine dicarboxylic acid dimethyl ester]is dissolved in a polyethylene glycol having an average molecular weight of 200-600 to the highest concentration possible. The solution is infiltrated into a porous carrier which can...