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Pfizer Inc.(549)
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[IPC] 包含 'C'
[专利权人] 包含 'Pfizer Inc.'
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549
条记录, 当前第1/55页。
公开号
公开日
申请号
申请日
1.
US8258315B2
2012/9/4
US13/079376
2011/4/4
专利标题
:Process for forming amorphous atorvastatin
专利权人
:
Pfizer Inc.
;
A process for forming amorphous atorvastatin comprising the steps of dissolving atorvastatin in a non-hydroxylic solvent and removing the solvent by freeze-drying as well as processes of dissolving atorvastatin in a hydroxylic solvent with a solubilizing agent or an alkalizing agent or an antioxidant and removing the solvent by freeze-drying to afford amorphous atorvastatin.
2.
US8044227B2
2011/10/25
专利标题
:Preparation of pregabalin and related compounds
专利权人
:
Pfizer Inc.
;
Materials and methods for preparing (S)-(+)-3-aminomethyl-5-methyl-hexanoic acid and structurally related compounds via enzymatic kinetic resolution are disclosed.
3.
US7939675B2
2011/5/10
US11/666707
2005/10/12
专利标题
:Process for forming amorphous atorvastatin
专利权人
:
Pfizer Inc.
;
A process for forming amorphous atorvastatin comprising the steps of dissolving atorvastatin in a non-hydroxylic solvent and removing the solvent by freeze-drying as well as processes of dissolving atorvastatin in a hydroxylic solvent with a solubilizing agent or an alkalizing agent or an antioxidant and removing the solvent by freeze-drying to afford amorphous atorvastatin.
4.
US7838686B2
2010/11/23
专利标题
:Preparation of pregabalin and related compounds
专利权人
:
Pfizer Inc.
;
Materials and Methods for preparing (S)-(+)-3-aminomethyl-5-methyl-hexanoic acid and structurally related compounds via enzymatic kinetic resolution are disclosed.
5.
CA2539297C
2010/7/20
CA20042539297
2004/9/10
专利标题
:Substituted triazole derivatives as oxytocin antagonists
专利权人
:
Pfizer Inc.
;
The present invention relates to a class of substituted 124-triazoles of formula (I) with activity as oxytocin antagonists uses thereof processes for the preparation thereof and compositions containing said inhibitors. These inhibitors have utility in a variety of therapeutic areas including sexual dysfunction particularly premature ejaculation (P.E.).
6.
IL152925A
2010/4/15
专利标题
:Pharmaceutical compositions for treatment of neuropathy comprising an inhibitor of cyclic guanosine 3',5'-monophosphate phosphodiesterase 5 and either gabapentin or pregabalin
专利权人
:
Pfizer Inc.
;
7.
CA2475712C
2009/11/24
CA20032475712
2003/2/3
专利标题
:Nicotinamide derivatives useful as pde4 inhibitors
专利权人
:
Pfizer Inc.
;
The invention relates to nicotinamide derivatives of formula (1) and to processes for the preparation of intermediates used in the preparation of compositions containing and the uses of such derivatives. The nicotinamide derivatives according to the present invention are phosphodiesterase-4 inhibitors and are useful in numerous diseases disorders and ( conditions in particular inflammatory allergic respiratory diseases disorders and conditions as well as wounds.
8.
WO2009081246A3
2009/9/3
专利标题
:Bicyclic diamines as nicotinic receptor agonists
专利权人
:
Pfizer Inc.
;
Compounds; pharmaceutically acceptable salts thereof; and stereoisomers of the compound of Formula I and pharmaceutically acceptable salts thereof; are disclosed wherein the compounds have the structure of Formula (I) as defined in the specification. Corresponding pharmaceutical compositions and methods of treatment are also disclosed.
9.
US20090221839A1
2009/9/3
US12/065555
2008/9/3
专利标题
:Preparation of an atorvastatin intermediate
专利权人
:
Pfizer Inc.
;
Atorvastatin lactone is prepared by hydrogenating tert-butyl isopropylidene nitrile to tert-butyl isopropylidene amine and condensing the amine with the diketone of atorvastatin to form acetonide ester. The diol protecting acetonide ester is deprotected to form a diol ester by dissolving the acetonide ester in methanol and treating with an acid. The diol ester is saponified to form a sodium salt. Methanol is removed from the reaction mixture by distillation. The sodium salt is reacidified to the...
10.
US20090221852A1
2009/9/3
专利标题
:Preparation of an atorvastatin intermediate
专利权人
:
Pfizer Inc.
;
The diketone of atorvastatin is prepared by first washing a reaction vessel with a non-ketonic solvent especially tetrahydrofuran to remove water. 4-fluorobenzaldehyde is then reacted with benzylidine isobutyryl acetanilide in the reaction vessel to form 4-fluoro-alpha-(2-methyl-1-oxopropyl)-gamma-oxo-Nbeta-diphenylbenzene-butanainide
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