A process for freeze drying an aqueous solution of a dosage amount of cyclophosphamide to yield a hydrate of cyclophosphamide ("CPA") comprises, in a first stage, freeze drying a solution of CPA with an excipient until the moisture content of the freeze-dried material is less than 2% by weight, based on anhydrous CPA present

An improved pharmaceutical or veterinary composition contains galactitol as carrier for the therapeutic agent. Preferred therapeutic agents include anti-infective and anti-cancer drugs, preferably cytotoxic agents and lymphokines. One example is a lyophilized composition of about 20 parts by weight of cyclophosphamide, taken as the anhydride, about 5 to 21 parts by weight of galactitol as excipient, and about 1.4 to 3 parts by weight of water. Preferably, the amount of galactitol is 15-21 parts ...