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H. Lundbeck A/s(1259)
专利信息
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[专利权人] 包含 'H. Lundbeck A/s'
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1259
条记录, 当前第1/126页。
公开号
公开日
申请号
申请日
1.
US8664225B2
2014/3/4
专利标题
:1-[2-(2,4-dimethylphenylsulfanyl)-phenyl] piperazine as a compound with combined serotonin reuptake, 5-ht3 and 5-ht1a activity for the treatment of pain or residual symptoms in depression relating to sleep and cognition
专利权人
:
H. Lundbeck A/s
;
The use of 1-[2-(24-dimethylphenylsulfanyl)phenyl]piperazine in the treatment of pain and residual symptoms in depression is provided.
2.
EA019331B1
2014/2/28
EA20110071461
2010/5/21
专利标题
:Preparation of nalmefene hydrochloride from naltrexone
专利权人
:
H. Lundbeck A/s
;
Method for producing nalmefene hydrochloride from naltrexone which method is particular well adapted for large-scale industrial application and has been found to be efficient to give a high yield and to afford highly pure nalmefene hydrochloride salt.
3.
US20140044806A1
2014/2/13
专利标题
:New positive allosteric modulators of nicotinic acetylcholine receptor
专利权人
:
H. Lundbeck A/s
;
The present invention relates to compounds useful in therapy to compositions comprising said compounds and to methods of treating diseases comprising administration of said compounds. The compounds referred to are positive allosteric modulators (PAMs) of the nicotinic acetylcholine alpha7 receptor.
4.
US20140010897A1
2014/1/9
专利标题
:New positive allosteric modulators of nicotinic acetylcholine receptor
专利权人
:
H. Lundbeck A/s
;
The present invention relates to compounds useful in therapy to compositions comprising said compounds and to methods of treating diseases comprising administration of said compounds. The compounds referred to are positive allosteric modulators (PAMs) of the nicotinic acetylcholine alpha7 receptor.
5.
US20140010898A1
2014/1/9
专利标题
:New positive allosteric modulators of nicotinic acetylcholine receptor
专利权人
:
H. Lundbeck A/s
;
The present invention relates to compounds useful in therapy to compositions comprising said compounds and to methods of treating diseases comprising administration of said compounds. The compounds referred to are positive allosteric modulators (PAMs) of the nicotinic acetylcholine alpha7 receptor.
6.
WO2014006120A1
2014/1/9
专利标题
:New positive allosteric modulators of nicotinic acetylcholine receptor
专利权人
:
H. Lundbeck A/s
;
The present invention relates to compounds according to formula (I) wherein R1 R2 R3 R4 and R5 are H; R6 is selected from methyl and hydroxymethyl; A7 is C-R7 A8 is N and A9 is C-R9; R7 R10 and R11 are H; R9 is OR12 wherein R12 represents a monocyclic saturated ring moiety having 4-6 ring atoms wherein one of said ring atoms is O and the rest is C; and pharmaceutically acceptable salts thereof useful in therapy to compositions comprising said compounds and to methods of treating diseases compris...
7.
WO2014006117A1
2014/1/9
专利标题
:New positive allosteric modulators of nicotinic acetylcholine receptor
专利权人
:
H. Lundbeck A/s
;
The present invention relates to compounds according to formula (I) wherein R1 R2 R3 R4 and R5 are H; R6 is methoxymethyl; A7 is C-R7 A8 is N and A9 is C-R9; R7 R9 R10 and R11 are selected independently of each other from H C1-6alkyl C2-6alkenyl C2-6alkynyl C1-6alkoxy and OR12; wherein R12 represents a monocyclic saturated ring moiety having 4-6 ring atoms wherein one of said ring atoms is and the rest is C; and pharmaceutically acceptable salts thereof useful in therapy to compositions comprisi...
8.
US20130331575A1
2013/12/12
专利标题
:Method for resolution of 4-((1r,3s)-6-chloro-3-phenyl-indan-1-yl)-1,2,2-trimethyl-piperazine and 1-((1r,3s)-6-chloro-3-phenyl-indan-1-yl)-3,3-dimethyl-piperazine
专利权人
:
H. Lundbeck A/s
;
The present invention relates to resolution methods for manufacture of 4-((1R3S)-6-chloro-3-phenyl-indan-1-yl)-122-trimethyl-piperazine and 1-((1R3S)-6-chloro-3-phenyl-indan-1-yl)-33-dimethyl-piperazine and pharmaceutically acceptable salts thereof.
9.
US8598352B2
2013/12/3
US13/321597
2010/5/21
专利标题
:Preparation of nalmefene hydrochloride from naltrexone
专利权人
:
H. Lundbeck A/s
;
Method for producing nalmefene hydrochloride from naltrexone which method is particular well adapted for large-scale industrial application and has been found to be efficient to give a high yield and to afford highly pure nalmefene hydrochloride salt.
10.
US8598348B2
2013/12/3
专利标题
:Purification of 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine
专利权人
:
H. Lundbeck A/s
;
The present invention concerns a process for the manufacture of 1-[2-(24-dimethylphenylsulfanyl)phenyl]piperazine.
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