Compounds of formula (1) wherein R1 is 2-indanyl R2 is 1-methylpropyl R3 is 2-methyl-13-oxazol-4-yl and R4 and R5 together with the nitrogen atom to which they are attached represents morpholino process for their preparation pharmaceutical compositions containing them and their use in medicine.

A succinic acid salt of biphenyl-2-ylcarbamic acid 1-[2-(2-chloro-4-{ [(R)-2-hydroxy-2 -(8-hydroxy-2-oxo-12-dihydroquinolin-5-yl)ethylamino]methyl}-5-methoxyphenyIcarbamoyl) ethyl]piperidin-4-yl ester of Formula I or a solvate thereof for use in treating pulmonary disorders. (see formula I)

Disclosed herein is novel process for preparation of atovaquone which process includes reacting 1H-2-benzopyran-14(3H)-dione with 4-(4-chlorophenyl)cyclohexanecarbaldehyde. The invention further discloses novel intermediates useful in the preparation of atovaquone.

Disclosed herein is novel process for preparation of atovaquone which process includes reacting 1H-2-benzopyran-14(3H)-dione with 4-(4-chlorophenyl)cyclohexanecarbaldehyde. The invention further discloses novel intermediates useful in the preparation of atovaquone.

A method of treating or preventing diseases or conditions mediated through the action of oxytocin which comprises administering to a human in need thereof of an effective amount of a compound of the formula (I) or a pharmaceutically acceptable salt thereof.

This invention relates to modulation of the 7 nicotinic acetylcholine receptor (nAChR) by a compound of formula (I) or a salt thereof.

A method of treating or preventing diseases or conditions mediated through the action of oxytocin which comprises administering to a human in need thereof of an effective amount of a compound of the formula (I) or a pharmaceutically acceptable salt thereof.

Compounds of formula (1) wherein R1 is 2-indanyl R2 is 1-methylpropyl R3 is 2-methyl-13-oxazol-4-yl and R4 and R5 together with the nitrogen atom to which they are attached represents morpholino process for their preparation pharmaceutical compositions containing them and their use in medicine.

A method of treating or preventing diseases or conditions mediated through the action of oxytocin which comprises administering to a mammal in need thereof of an effective amount of a compound of the formula (I)and/or a physiologically acceptable derivative thereof wherein the substituents have the meaning given in the description. Disclosed are also novel compounds of formula (I) and processes for their preparation.