专利信息

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专利标题：Methods of preparing substituted tetracyclines with transition metal-based chemistries

The present invention relates to novel chemistries which allow for heretofore unobtainable substituted tetracycline compounds which exhibit significant activity in tetracycline responsive states. The methods disclosed herein utilize reactive tetracycline-based precursor compounds reactive organic substituent precursors and transition metal catalysts under conditions such that a tetracycline compound substituted with the desired organic substituent is formed. In one embodiment of the invention a ...

专利标题：Substituted tetracycline compounds

The present invention pertains at least in part to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states such as bacterial infections and neoplasms.

专利标题：9-substituted minocycline compounds

The present invention pertains at least in part to novel 9-substituted minocycline compounds. These minocycline compounds can be used to treat numerous tetracycline compound-responsive states such as bacterial infections and neoplasms as well as other known applications for minocycline and tetracycline compounds in general such as blocking tetracycline efflux and modulation of gene expression.

专利标题：7-pyrazolyl tetracycline compounds and methods of use thereof

The present invention provides compounds of Formula (I) and related methods and formulations: wherein: A represents a pyrazole ring optionally substituted by one or more R groups.

专利标题：7-n-substituted phenyl tetracycline compounds

7-substituted tetracycline compounds methods of treating tetracycline responsive states and pharmaceutical compositions containing the 7-substituted tetracycline compounds are described.

专利标题：7-iodo tetracyclines and related methods

7-substituted fused ring tetracycline compounds methods of treating tetracycline responsive states and pharmaceutical compositions containing the 7-substituted fused ring tetracycline compounds are described.

专利标题：Methods of using substituted tetracycline compounds to modulate rna

A method for modulating RNA with tetracycline compounds is described.

专利标题：9-substituted minocycline compounds

专利标题：7, 8 and 9-substituted tetracycline compounds

7 8 and 9-substituted tetracycline compounds methods of treating tetracycline responsive states and pharmaceutical compositions containing the 7 8 and 9-substituted tetracycline compounds are described.

专利标题：7-pyrollyl 9-aminoacyl tetracycline compounds and methods of use thereof

A compound of formula (I): wherein: A represents an aromatic 5 membered heterocycle optionally containing in addition to the nitrogen atom indicated in formula (I) one to three additional nitrogen atoms.

当前查询条件: [专利权人] 包含 'Mintz Levin Cohn Ferris Glovsky And Popeo Pc' AND [药品] 包含 'Tetracycline'

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!	专利类型	发明实用新型外观设计
!	公开号			CN1234
!	申请号			CN1234
!	专利标题		扩展	PHARMA
!	专利权人		扩展	pfizer
	发明人
!	申请日			yyyymmdd
!	公开日			yyyymmdd
	优先权号
!	摘要		扩展	PHARMA
	IPC			A01B

1. US20130029943A1	2013/1/31	US13/312291	2011/12/6
专利标题：Methods of preparing substituted tetracyclines with transition metal-based chemistries 专利权人：Mintz Levin Cohn Ferris Glovsky And Popeo Pc; The present invention relates to novel chemistries which allow for heretofore unobtainable substituted tetracycline compounds which exhibit significant activity in tetracycline responsive states. The methods disclosed herein utilize reactive tetracycline-based precursor compounds reactive organic substituent precursors and transition metal catalysts under conditions such that a tetracycline compound substituted with the desired organic substituent is formed. In one embodiment of the invention a ...

2. US8318706B2	2012/11/27	US11/963540	2007/12/21
专利标题：Substituted tetracycline compounds 专利权人：Mintz Levin Cohn Ferris Glovsky And Popeo Pc; The present invention pertains at least in part to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states such as bacterial infections and neoplasms.

3. US20120283201A1	2012/11/8	US13/547870	2012/7/12
专利标题：9-substituted minocycline compounds 专利权人：Mintz Levin Cohn Ferris Glovsky And Popeo Pc; The present invention pertains at least in part to novel 9-substituted minocycline compounds. These minocycline compounds can be used to treat numerous tetracycline compound-responsive states such as bacterial infections and neoplasms as well as other known applications for minocycline and tetracycline compounds in general such as blocking tetracycline efflux and modulation of gene expression.

4. US8304445B2	2012/11/6	US13/038102	2011/3/1
专利标题：7-pyrazolyl tetracycline compounds and methods of use thereof 专利权人：Mintz Levin Cohn Ferris Glovsky And Popeo Pc; The present invention provides compounds of Formula (I) and related methods and formulations: wherein: A represents a pyrazole ring optionally substituted by one or more R groups.

5. US8293931B2	2012/10/23	US13/173968	2011/6/30
专利标题：7-n-substituted phenyl tetracycline compounds 专利权人：Mintz Levin Cohn Ferris Glovsky And Popeo Pc; 7-substituted tetracycline compounds methods of treating tetracycline responsive states and pharmaceutical compositions containing the 7-substituted tetracycline compounds are described.

6. US8288570B2	2012/10/16	US13/031075	2011/2/18
专利标题：7-iodo tetracyclines and related methods 专利权人：Mintz Levin Cohn Ferris Glovsky And Popeo Pc; 7-substituted fused ring tetracycline compounds methods of treating tetracycline responsive states and pharmaceutical compositions containing the 7-substituted fused ring tetracycline compounds are described.

7. US20120245130A1	2012/9/27	US13/426408	2012/3/21
专利标题：Methods of using substituted tetracycline compounds to modulate rna 专利权人：Mintz Levin Cohn Ferris Glovsky And Popeo Pc; A method for modulating RNA with tetracycline compounds is described.

8. US8258120B2	2012/9/4	US12/351405	2009/1/9
专利标题：9-substituted minocycline compounds 专利权人：Mintz Levin Cohn Ferris Glovsky And Popeo Pc; The present invention pertains at least in part to novel 9-substituted minocycline compounds. These minocycline compounds can be used to treat numerous tetracycline compound-responsive states such as bacterial infections and neoplasms as well as other known applications for minocycline and tetracycline compounds in general such as blocking tetracycline efflux and modulation of gene expression.

9. US8252777B2	2012/8/28	US13/012590	2011/1/24
专利标题：7, 8 and 9-substituted tetracycline compounds 专利权人：Mintz Levin Cohn Ferris Glovsky And Popeo Pc; 7 8 and 9-substituted tetracycline compounds methods of treating tetracycline responsive states and pharmaceutical compositions containing the 7 8 and 9-substituted tetracycline compounds are described.

10. US8211937B2	2012/7/3	US11/949392	2007/12/3
专利标题：7-pyrollyl 9-aminoacyl tetracycline compounds and methods of use thereof 专利权人：Mintz Levin Cohn Ferris Glovsky And Popeo Pc; A compound of formula (I): wherein: A represents an aromatic 5 membered heterocycle optionally containing in addition to the nitrogen atom indicated in formula (I) one to three additional nitrogen atoms.

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