专利信息

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专利标题：Positive allosteric modulators of nicotinic acetylcholine receptor

专利权人：H. Lundbeck A/s;

The present invention relates to compounds useful in therapy to compositions comprising said compounds and to methods of treating diseases comprising administration of said compounds. The compounds referred to are positive allosteric modulators (PAMs) of the nicotinic acetylcholine alpha7 receptor.

专利标题：Purification of 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]-piperazine

专利权人：H. Lundbeck A/s;

专利标题：Positive allosteric modulators of nicotinic acetylcholine receptor

专利权人：H. Lundbeck A/s;

The present invention relates to compounds of formula (I) useful in therapy to compositions comprising said compounds and to methods of treating diseases comprising administration of said compounds. The compounds referred to are positive allosteric modulators (PAMs) of the nicotinic acetylcholine α7 receptor.

专利标题：Method for the manufacturing of naltrexone

专利权人：H. Lundbeck A/s;

The present invention relates to an improved process for producing naltrexone[17-(cyclopropylmethyl)-45alpha-epoxy-314-dihydroxy-morphinan-6-one] from noroxymorphone[45-alpha-epoxy-314-dihydroxy-morphinan-6-one] by alkylation with a cyclopropylmethyl halide.

专利标题：Method for the manufacturing of naltrexone

专利权人：H. Lundbeck A/s;

The present invention relates to a new process for producing naltrexone [17-(cyclopropylmethyl)-45α-epoxy-314-dihydroxy-morphinan-6-one] from noroxymorphone [45- α-epoxy-314-dihydroxy-morphinan-6-one] by alkylation with a cyclopropylmethyl halide.

专利标题：Process for the preparation of racemic citalopram and/or s- or r-citalopram by separation of a mixture of r- and s-citalopram

专利权人：H. Lundbeck A/s;

The invention relates to a process for the preparation of racemic citalopram free base or an acid addition salt thereof and/or R- or S-citalopram as the free base of an acid addition salt thereof by separation of a mixture of R- and S-citalopram with more than 50% of one of the enantiomers into a fraction consisting of racemic citalopram and/or a fraction of S-citalopram or R-citalopram characterised in that (i) citalopram is precipitated from a solvent as the free base or as an acid addition sa...

专利标题：Heteroaromatic aryl triazole derivatives as pde10a enzyme inhibitors

专利权人：H. Lundbeck A/s;

600416 Disclosed are 5-bicycloheteroarylalkyl-3-phenyl-124-triazole derivatives as represented by the general formula (I) wherein: HET-1 is a heteroaromatic group of formula II containing from 2 to 4 nitrogen atoms and which is preferably selected from [124]triazolo[15-a]pyridine [124]triazolo[15-a]pyrimidine or [124]triazolo[15-a]pyrazine and which may be optionally substituted; Q is phenyl optionally substituted with one to five substituents or a monocyclic 5-membered or 6-membered heteroaroma...

专利标题：Method for the manufacturing of naltrexone

专利权人：H. Lundbeck A/s;

专利标题：2-arylimidazole derivatives as pde10a enzyme inhibitors

专利权人：H. Lundbeck A/s;

600416 Disclosed are 4-bicycloheteroarylalkyl-2-phenyl-imidazole derivatives as represented by the general formula (I) wherein: HET-1 is a heteroaromatic group of formula II containing from 2 to 4 nitrogen atoms and which is preferably selected from [124]triazolo[15-a]pyrazine or [124]triazolo[15-a]pyridine and which may be optionally substituted; Q is phenyl optionally substituted with one to five substituents or a monocyclic 5-membered or 6-membered heteroaromatic group containing 1 or 2 heter...

专利标题：Combination of a serotonin reuptake inhibitor and agomelatine

专利权人：H. Lundbeck A/s;

The present invention relates to the use of a combination of agomelatine and a serotonin reuptake inhibitor (SRIs) or any other compound which causes an elevation in the level of extracellular serotonin for the treatment of depression and other affective disorders.

当前查询条件: [专利权人] 包含 'H. Lundbeck A/s'

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!	公开号			CN1234
!	申请号			CN1234
!	专利标题		扩展	PHARMA
!	专利权人		扩展	pfizer
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!	申请日			yyyymmdd
!	公开日			yyyymmdd
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!	摘要		扩展	PHARMA
	IPC			A01B

1. US8598213B2	2013/12/3
专利标题：Positive allosteric modulators of nicotinic acetylcholine receptor 专利权人：H. Lundbeck A/s; The present invention relates to compounds useful in therapy to compositions comprising said compounds and to methods of treating diseases comprising administration of said compounds. The compounds referred to are positive allosteric modulators (PAMs) of the nicotinic acetylcholine alpha7 receptor.

2. EP2398785B1	2013/11/27
专利标题：Purification of 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]-piperazine 专利权人：H. Lundbeck A/s;

3. AU2012283208A1	2013/11/21
专利标题：Positive allosteric modulators of nicotinic acetylcholine receptor 专利权人：H. Lundbeck A/s; The present invention relates to compounds of formula (I) useful in therapy to compositions comprising said compounds and to methods of treating diseases comprising administration of said compounds. The compounds referred to are positive allosteric modulators (PAMs) of the nicotinic acetylcholine α7 receptor.

4. US8580963B2	2013/11/12	US13/287391	2011/11/2
专利标题：Method for the manufacturing of naltrexone 专利权人：H. Lundbeck A/s; The present invention relates to an improved process for producing naltrexone[17-(cyclopropylmethyl)-45alpha-epoxy-314-dihydroxy-morphinan-6-one] from noroxymorphone[45-alpha-epoxy-314-dihydroxy-morphinan-6-one] by alkylation with a cyclopropylmethyl halide.

5. WO2013164383A1	2013/11/7	WO2013EP59104	2013/5/2
专利标题：Method for the manufacturing of naltrexone 专利权人：H. Lundbeck A/s; The present invention relates to a new process for producing naltrexone [17-(cyclopropylmethyl)-45α-epoxy-314-dihydroxy-morphinan-6-one] from noroxymorphone [45- α-epoxy-314-dihydroxy-morphinan-6-one] by alkylation with a cyclopropylmethyl halide.

6. BG66372B1	2013/10/31
专利标题：Process for the preparation of racemic citalopram and/or s- or r-citalopram by separation of a mixture of r- and s-citalopram 专利权人：H. Lundbeck A/s; The invention relates to a process for the preparation of racemic citalopram free base or an acid addition salt thereof and/or R- or S-citalopram as the free base of an acid addition salt thereof by separation of a mixture of R- and S-citalopram with more than 50% of one of the enantiomers into a fraction consisting of racemic citalopram and/or a fraction of S-citalopram or R-citalopram characterised in that (i) citalopram is precipitated from a solvent as the free base or as an acid addition sa...

7. NZ600365A	2013/10/25	NZ20100600365	2010/12/15
专利标题：Heteroaromatic aryl triazole derivatives as pde10a enzyme inhibitors 专利权人：H. Lundbeck A/s; 600416 Disclosed are 5-bicycloheteroarylalkyl-3-phenyl-124-triazole derivatives as represented by the general formula (I) wherein: HET-1 is a heteroaromatic group of formula II containing from 2 to 4 nitrogen atoms and which is preferably selected from [124]triazolo[15-a]pyridine [124]triazolo[15-a]pyrimidine or [124]triazolo[15-a]pyrazine and which may be optionally substituted; Q is phenyl optionally substituted with one to five substituents or a monocyclic 5-membered or 6-membered heteroaroma...

8. EP2635586A1	2013/9/11	EP20110785301	2011/11/4
专利标题：Method for the manufacturing of naltrexone 专利权人：H. Lundbeck A/s;

9. NZ600416A	2013/8/30	NZ20100600416	2010/12/15
专利标题：2-arylimidazole derivatives as pde10a enzyme inhibitors 专利权人：H. Lundbeck A/s; 600416 Disclosed are 4-bicycloheteroarylalkyl-2-phenyl-imidazole derivatives as represented by the general formula (I) wherein: HET-1 is a heteroaromatic group of formula II containing from 2 to 4 nitrogen atoms and which is preferably selected from [124]triazolo[15-a]pyrazine or [124]triazolo[15-a]pyridine and which may be optionally substituted; Q is phenyl optionally substituted with one to five substituents or a monocyclic 5-membered or 6-membered heteroaromatic group containing 1 or 2 heter...

10. US20130217776A1	2013/8/22	US13/552699	2012/7/19
专利标题：Combination of a serotonin reuptake inhibitor and agomelatine 专利权人：H. Lundbeck A/s; The present invention relates to the use of a combination of agomelatine and a serotonin reuptake inhibitor (SRIs) or any other compound which causes an elevation in the level of extracellular serotonin for the treatment of depression and other affective disorders.

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