专利信息

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专利标题：Neue zur synthese von s- und r-omeprazol geeignete verbindungen und ein verfahren zu deren herstellung

专利权人：ASTRAZENECA AB;

专利标题：Method for treating a patient at risk for developing an nsaid-associated ulcer.

专利权人：ASTRAZENECA AB;

The present disclosure is directed to a method for treating a disease or disorder in a patient at risk of developing an NSAID-associated ulcer by administering a pharmaceutical composition in unit dose form comprising naproxen or pharmaceutically acceptable salt thereof and esomeprazole or pharmaceutically acceptable salt thereof. The unit dose is designed to release at least a part of the esomeprazole independent of pH (e.g. at a pH of 0 or more) whereas the naproxen is not released until the p...

专利标题：Method for treating a patient at risk for developing an nsaid-associated ulcer

专利权人：ASTRAZENECA AB;

专利标题：Intermediates and processes for the preparation of 4- (acetylamino) ) -3- [ (4-chloro-phenyl) thio] -2-methyl-1H-indole-1-acetic acid

专利权人：ASTRAZENECA AB;

The invention relates to compounds of formula (X), and salts thereof, and their use as intermediates in improved manufacturing processes for the synthesis of pharmaceutical compound of formula (I): X is =0, =N-0H or =N-OC(O)Me

专利标题：Method, midbody and the crystalline salt thereof of preparation 4-(6-chloro-2,3-methylenedioxyphenyl amido)-7-[2-(4-n-methyl piperazine-1-yl) oxyethyl group]-5-tetrahydropyran-4-base oxygen base quinazoline

专利权人：ASTRAZENECA AB;

专利标题：Derivados de (4-terc-butilpiperazin-2-il)(piperazin-1-il)metanona-n-carboxamida

专利权人：ASTRAZENECA AB;

La presente invención se refiere a compuestos de fórmula (I) ESPACIO PARA LA FÓRMULA Los compuestos actúan a través del antagonismo del receptor CCR2b y pueden utilizarse para tratar una enfermedad inflamatoria y/o el dolor neuropático.

专利标题：Diarylmethyl piperazine derivatives, preparations thereof and uses thereof

专利权人：ASTRAZENECA AB;

专利标题：New compounds useful for the synthesis of s- and r-omeprazole and a process for their preparation

专利权人：ASTRAZENECA AB;

The present invention relates to an improved method for the synthesis of the (S)- or (R)- enantiomer of omeprazole characterized in that 2-[[(4-X-35-dimethylpyridin-2-yl)methyl]thio]-5-methoxy-1H-benzimidazole or 2-[[(4-X-35-dimethyl-1-oxidopyridin-2-yl)methyl]thio]-5-methoxy-1H-benzimidazole wherein X is a leaving group is oxidized into the corresponding sulphoxide which is obtained as a crystalline compound. Recrystallisation of the thus obtained sulphoxide results in a compound of enhanced ch...

专利标题：Antibacterial polycyclic urea compounds

专利权人：ASTRAZENECA AB;

Disclosed are pyridine or pyrimidine amide derivatives of a compound of general formula (XVIII) wherein the other substituents are disclosed within the specification. Also disclosed is the use of the compounds for treating an antibacterial infection such as community-acquired pneumoniae hospital-acquired pneumoniae skin and skin structure infections acute exacerbation of chronic bronchitis acute sinusitis acute otitis media catheter related sepsis febrile neutropenia osteomyelitis endocarditis u...

专利标题：(4-tertiary butyl piperazine-2-yl) (piperazine-1-yl) ketone-n-carboxamides derivatives

专利权人：ASTRAZENECA AB;

当前查询条件: [专利权人] 包含 'ASTRAZENECA AB'

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!	专利类型	发明实用新型外观设计
!	公开号			CN1234
!	申请号			CN1234
!	专利标题		扩展	PHARMA
!	专利权人		扩展	pfizer
	发明人
!	申请日			yyyymmdd
!	公开日			yyyymmdd
	优先权号
!	摘要		扩展	PHARMA
	IPC			A01B

1. AT541838T	2012/2/15
专利标题：Neue zur synthese von s- und r-omeprazol geeignete verbindungen und ein verfahren zu deren herstellung 专利权人：ASTRAZENECA AB;

2. MX2011013467A	2012/2/13	MX20110013467	2011/12/13
专利标题：Method for treating a patient at risk for developing an nsaid-associated ulcer. 专利权人：ASTRAZENECA AB; The present disclosure is directed to a method for treating a disease or disorder in a patient at risk of developing an NSAID-associated ulcer by administering a pharmaceutical composition in unit dose form comprising naproxen or pharmaceutically acceptable salt thereof and esomeprazole or pharmaceutically acceptable salt thereof. The unit dose is designed to release at least a part of the esomeprazole independent of pH (e.g. at a pH of 0 or more) whereas the naproxen is not released until the p...

3. AU2010263304A1	2012/2/2	AU20100263304	2010/6/23
专利标题：Method for treating a patient at risk for developing an nsaid-associated ulcer 专利权人：ASTRAZENECA AB; The present disclosure is directed to a method for treating a disease or disorder in a patient at risk of developing an NSAID-associated ulcer by administering a pharmaceutical composition in unit dose form comprising naproxen or pharmaceutically acceptable salt thereof and esomeprazole or pharmaceutically acceptable salt thereof. The unit dose is designed to release at least a part of the esomeprazole independent of pH (e.g. at a pH of 0 or more) whereas the naproxen is not released until the p...

4. AU2010270050A1	2012/2/2	AU20100270050	2010/7/5
专利标题：Intermediates and processes for the preparation of 4- (acetylamino) ) -3- [ (4-chloro-phenyl) thio] -2-methyl-1H-indole-1-acetic acid 专利权人：ASTRAZENECA AB; The invention relates to compounds of formula (X), and salts thereof, and their use as intermediates in improved manufacturing processes for the synthesis of pharmaceutical compound of formula (I): X is =0, =N-0H or =N-OC(O)Me

5. CN101115744B	2012/2/1
专利标题：Method, midbody and the crystalline salt thereof of preparation 4-(6-chloro-2,3-methylenedioxyphenyl amido)-7-[2-(4-n-methyl piperazine-1-yl) oxyethyl group]-5-tetrahydropyran-4-base oxygen base quinazoline 专利权人：ASTRAZENECA AB;

6. CU20110133A7	2012/1/31
专利标题：Derivados de (4-terc-butilpiperazin-2-il)(piperazin-1-il)metanona-n-carboxamida 专利权人：ASTRAZENECA AB; La presente invención se refiere a compuestos de fórmula (I) ESPACIO PARA LA FÓRMULA Los compuestos actúan a través del antagonismo del receptor CCR2b y pueden utilizarse para tratar una enfermedad inflamatoria y/o el dolor neuropático.

7. EP1781631B1	2012/1/25
专利标题：Diarylmethyl piperazine derivatives, preparations thereof and uses thereof 专利权人：ASTRAZENECA AB;

8. EP1718636B1	2012/1/18	EP20050711081	2005/2/17
专利标题：New compounds useful for the synthesis of s- and r-omeprazole and a process for their preparation 专利权人：ASTRAZENECA AB; The present invention relates to an improved method for the synthesis of the (S)- or (R)- enantiomer of omeprazole characterized in that 2-[[(4-X-35-dimethylpyridin-2-yl)methyl]thio]-5-methoxy-1H-benzimidazole or 2-[[(4-X-35-dimethyl-1-oxidopyridin-2-yl)methyl]thio]-5-methoxy-1H-benzimidazole wherein X is a leaving group is oxidized into the corresponding sulphoxide which is obtained as a crystalline compound. Recrystallisation of the thus obtained sulphoxide results in a compound of enhanced ch...

9. NZ578159A	2012/1/12	NZ20070578159	2007/12/3
专利标题：Antibacterial polycyclic urea compounds 专利权人：ASTRAZENECA AB; Disclosed are pyridine or pyrimidine amide derivatives of a compound of general formula (XVIII) wherein the other substituents are disclosed within the specification. Also disclosed is the use of the compounds for treating an antibacterial infection such as community-acquired pneumoniae hospital-acquired pneumoniae skin and skin structure infections acute exacerbation of chronic bronchitis acute sinusitis acute otitis media catheter related sepsis febrile neutropenia osteomyelitis endocarditis u...

10. CN102317273A	2012/1/11
专利标题：(4-tertiary butyl piperazine-2-yl) (piperazine-1-yl) ketone-n-carboxamides derivatives 专利权人：ASTRAZENECA AB;

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