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标题标题2专利权人发明人附图摘要摘要2优先权号IPC专利类型
首页上页1234567下页尾页1619 条记录, 当前第2/162页。
公开号 公开日 申请号 申请日
1. AU2012231547A8 2013/10/24 AU20120231547 2012/3/22
专利标题:New crystal form vii of agomelatine, preparation method and use thereof and pharmaceutical composition containing same 法律状态
专利权人LES LABORATOIRES SERVIER;
The present invention provides a new crystal form VII of agomelatine the preparation method and use thereof and a pharmaceutical composition containing the same. The new crystal form has a good purity a stable crystal form and good reproducibility; the preparation method thereof is easy to amplify; and it is superior to most previously reported crystal forms in terms of stability and solubility. Therefore the crystal form VII of the present invention has an advantage in terms of preparation.


2. US20130267738A1 2013/10/10 US13/702388 2011/6/8
专利标题:Agomelatine intermediates and preparation method thereof 法律状态
专利权人LES LABORATOIRES SERVIER;
The present invention relates to the intermediate compounds for preparation of agomelatine as well as the preparation methods thereof. The intermediate of the present invention for preparation of agomelatine is compound A as shown in the following formula. Also provided are two novel intermediate compounds. When we use these new intermediate compounds to prepare agomelatine it is simple to manipulate well-controlled and with high purity without complicated operations such as rectification and co...


3. HU229188B1 2013/9/30 HU20010001335 2001/3/30
专利标题:Process for the preparation of n-[(s)-1-carboxybutyl]-(s)-alanine esters and their use for synthesizing perindopril 法律状态
专利权人LES LABORATOIRES SERVIER;
Stereoselective process for the industrial synthesis of compounds of formula (I):wherein R represents linear or branched (C1-C6)alkyl.Application in the synthesis of perindopril and pharmaceutically acceptable salts thereof.


4. HU229189B1 2013/9/30 HU20010001337 2001/3/30
专利标题:Process for the preparation of n-[(s)-1-carboxy-butyl]-(s)-alanine esters and their use for synthesizing perindopril 法律状态
专利权人LES LABORATOIRES SERVIER;
A stereoselective process for the industrial synthesis of compounds of formula (I):wherein R represents linear or branched (C1-C6)alkyl andapplication in the synthesis of perindopril and pharmaceutically acceptable salts thereof.


5. EP2547650A4 2013/9/18 EP20110755680 2011/3/17
专利标题:Agomelatine hydrobromide hydrate and preparation thereof 法律状态
专利权人LES LABORATOIRES SERVIER;


6. EP2612850B1 2013/9/18 EP20130150296 2013/1/4
专利标题:Delta crystalline form of the arginine salt of perindopril, a process for its preparation, and pharmaceutical compositions containing it 法律状态
专利权人LES LABORATOIRES SERVIER;
Delta crystalline form of perindopril L-arginine salt (I) having X-ray powder diffraction peaks measured using a diffractometer with a copper anticathode and expressed in terms of Bragg's angle 2 theta values as given in the specification is new. Independent claims are included for: (1) the preparation of delta crystalline form of (I); and (2) a composition comprising an active agent and the delta crystalline form of (I) in combination with carriers. ACTIVITY : Cardiovascular-Gen; Hypotensive; C...


7. AU2009202905B2 2013/9/5 AU20090202905 2009/7/16
专利标题:New process for the synthesis of agomelatine 法律状态
专利权人LES LABORATOIRES SERVIER;
NEW PROCESS FOR THE SYNTHESIS OF AGOMELATINE Abstract A process for the industrial synthesis of the compound of formula (1) is described. NHCOMe MeO "N (IM


8. AU2009203052B2 2013/9/5 AU20090203052 2009/7/27
专利标题:New process for the synthesis of agomelatine 法律状态
专利权人LES LABORATOIRES SERVIER;
NEW PROCESS FOR THE SYNTHESIS OF AGOMELATINE Abstract The invention relates to a process for the industrial synthesis of the compound of formula (1) NHCOMe MeO


9. AU2009203105B2 2013/9/5 AU20090203105 2009/7/29
专利标题:New process for the synthesis of agomelatine 法律状态
专利权人LES LABORATOIRES SERVIER;
NEW PROCESS FOR THE SYNTHESIS OF AGOMELATINE Abstract The invention relates to a process for the industrial synthesis of the compound of formula (1) NHCOMe MeO ()


10. EP2547649A4 2013/9/4 EP20110755679 2011/3/17
专利标题:Agomelatine hydrochloride hydrate and preparation thereof 法律状态
专利权人LES LABORATOIRES SERVIER;



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