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首页上页1234567891011下页尾页1619 条记录, 当前第6/162页。
公开号 公开日 申请号 申请日
1. FR2978916A1 2013/2/15 FR20110002500 2011/8/10
专利标题:Composition pharmaceutique solide pour administration buccale d'agomelatine 法律状态
专利权人LES LABORATOIRES SERVIER;
L'invention a pour objet une composition pharmaceutique buccale solide contenant de l'agomélatine destinée à une action systémique.


2. US20130041040A1 2013/2/14 US13/570626 2012/8/9
专利标题:Solid pharmaceutical composition for buccal administration of agomelatine 法律状态
专利权人LES LABORATOIRES SERVIER;
The invention relates to a solid buccal pharmaceutical composition comprising agomelatine intended for systemic action.


3. CA2695234C 2013/2/5 CA20082695234 2008/8/1
专利标题:Novel method for the synthesis of (7-methoxy-1-naphthyl)acetonitrile and application in the synthesis of agomelatine 法律状态
专利权人LES LABORATOIRES SERVIER;
Procédé de synthèse industrielle du composé de formule (I) Application à la synthèse de l'agomélatine.


4. AP201306659D0 2013/1/31 AP20130006659 2011/6/8
专利标题:Agomelatine intermediates and preparation method thereof 法律状态
专利权人LES LABORATOIRES SERVIER;


5. AP201306655D0 2013/1/31
专利标题:Process for the preparation of the l-arginine saltof perindopril 法律状态
专利权人LES LABORATOIRES SERVIER;


6. AP201306657D0 2013/1/31
专利标题:Delta crystalline form of the arginine salt of perindopril, a process for its preparation and pharmaceutical compositions containing it 法律状态
专利权人LES LABORATOIRES SERVIER;


7. EP2418195A4 2013/1/16 EP20100745836 2010/2/26
专利标题:Agomelatine hydrohalide complex and preparation method thereof 法律状态
专利权人LES LABORATOIRES SERVIER;


8. US20130012592A1 2013/1/10 US13/635087 2011/3/17
专利标题:Agomelatine hydrobromide hydrate and preparation thereof 法律状态
专利权人LES LABORATOIRES SERVIER;
The present invention relates to an agomelatine hydrobromide hydrate of formula I wherein X is Br preparation and use thereof and to pharmaceutical compositions containing it. The agomelatine hydrobromide hydrate obtained through the present method has significant increased solubility than agomelatine and therefore is more suitable for manufacturing pharmaceutical formulations. In addition the product enjoys higher stability and purity. Using the present method product of high purity can be obta...


9. AU2008243132B2 2013/1/10 AU20080243132 2008/11/6
专利标题:New crystalline form vi of agomelatine, a process for its preparation and pharmaceutical compositions containing it 法律状态
专利权人LES LABORATOIRES SERVIER;
NEW CRYSTALLINE FORM VI OF AGOMELATINE A PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT 5 Abstract The present invention relates to crystalline form VI of the compound of formula (I): NHCOMe MeO characterised by its X-ray powder diffraction diagram. The invention also relates to pharmaceutical compositions comprising crystalline form'VI of the compound of formula 10 (1) and to methods of treating disorders of the melatoninergic system.


10. CA2558764C 2013/1/8 CA20062558764 2006/9/8
专利标题:New association between agomelatine and a thymoregulator and the pharmaceutical compositions that contain it 法律状态
专利权人LES LABORATOIRES SERVIER;
La présente invention concerne une nouvelle association entre l'agomélatine ou N-[2-(7--méthoxy-1-naphtyl)éthyl]acétamide de formule (I) : (voir formule I) ou un de ses hydrates formes cristallines et sels d'addition à un acide ou à une base pharmaceutiquement acceptable et un agent thymorégulateur pour l'obtention de compositions pharmaceutiques utiles dans le traitement des troubles de l'humeur et plus particulièrement du trouble dépressif majeur du trouble cyclothymique et du trouble dysthymi...



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